What Does High Level Of TPO During Pregnancy Suggest?

Posted on Thu, 30 Jul 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 30 Jul 2015 Answered on

Wed, 26 Aug 2015 Last reviewed on

Question : Hello, I am pregnant 11 weeks an 3 days. I got pregnant in vitro. My OBY was worriers about my TPO at the beggining were 109.3 (normal level 0-10). I am pregnant with twins. My OBY was worried about high level of TPO and included in th 10mg prednisone. I am still taking it. Should I or not.
Thank you in advance

Answered by Dr. Ivo Ditah (1 hour later)

Brief Answer:
You should!

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about this elevated levels of TPO. This points to autoimmune disease of the thyroid. Am curious and will like to know what the TSH, T4 and T3 hormone levels was. This will shed more like on whether it is a full blown thyroid disease or not. It may also point the need for hormonal supplements or not.

Prednisone is not a big NO in pregnancy. As long as it is needed, it is recommended to use it. For how long have you been taking this drug and has there been any followup test to see what the levels of TPO are?

I hope this helps. I wish you well. Thanks for using our services and do feel free to ask for more information and clarifications if need be.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar