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What Does Increase In LDL Value Indicate?

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Posted on Sat, 20 Sep 2014
Twitter Sat, 20 Sep 2014 Answered on
Twitter Wed, 8 Oct 2014 Last reviewed on
Question : I went off a privastatin (20 mg) and my total LDL went from 123 to 170. How bad is that developement?MY PSA diagnostic XXXXXXX from 1.98 to 2.96 over 18 months. Does this require

further investigation?
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Answered by Dr. Shoaib Khan (1 hour later)
Brief Answer:
Need to reinitiate statins; need further tests

Detailed Answer:
Hello sir and welcome.

Thank you for writing to us.

I have gone through your query with diligence and would like you to know that I am here to help. I would first like to ask what the indication was to initiate the statins in your specific case sir? Do you have a history of cardiac abnormalities? A stroke? O just abnormally high cholesterol?

The reason why I ask this is because:
-Without any underlying condition, your LDL values will have to be below 130. Anything above 130 (especially a level of 170), puts you at an increased risk for coronary artery disease. We will have to bring your levels back to the normal range as soon as possible
-If you have other risk factors present (eg. obesity, smoker, etc.), then your LDL values have to ideally be below 100. A level of 170 is considered very unhealthy and can result in serious consequences quite soon.
-If you have a positive cardiac history, then your LDL value will have to be be below 70, and a level of 170 puts you at a very high risk (dangerously) to another cardiac event.

Please reinitiate statins, to help control your LDL levels. Also introduce mild forms of exercise and initiate a TLC diet at the earliest to help reduce the levels to a certain extent.

As for your PSA sir, as long as they are still within normal range (i.e. less than 3), there should be nothing to worry about. But as your levels are close to the lower limit of normal, I would recommend a repeat PSA level check within a month from the last test. Also, an ultrasound (more economic but less specific) or CT scan (less economic but more specific) will help determine any structural abnormalities to the prostate. I would say, that further investigation would be wise at this point.

I hope you find my response helpful sir. Please feel free to write back to me for any further clarifications, I would be more than happy to help you.

Best wishes sir.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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What Does Increase In LDL Value Indicate?

Brief Answer: Need to reinitiate statins; need further tests Detailed Answer: Hello sir and welcome. Thank you for writing to us. I have gone through your query with diligence and would like you to know that I am here to help. I would first like to ask what the indication was to initiate the statins in your specific case sir? Do you have a history of cardiac abnormalities? A stroke? O just abnormally high cholesterol? The reason why I ask this is because: -Without any underlying condition, your LDL values will have to be below 130. Anything above 130 (especially a level of 170), puts you at an increased risk for coronary artery disease. We will have to bring your levels back to the normal range as soon as possible -If you have other risk factors present (eg. obesity, smoker, etc.), then your LDL values have to ideally be below 100. A level of 170 is considered very unhealthy and can result in serious consequences quite soon. -If you have a positive cardiac history, then your LDL value will have to be be below 70, and a level of 170 puts you at a very high risk (dangerously) to another cardiac event. Please reinitiate statins, to help control your LDL levels. Also introduce mild forms of exercise and initiate a TLC diet at the earliest to help reduce the levels to a certain extent. As for your PSA sir, as long as they are still within normal range (i.e. less than 3), there should be nothing to worry about. But as your levels are close to the lower limit of normal, I would recommend a repeat PSA level check within a month from the last test. Also, an ultrasound (more economic but less specific) or CT scan (less economic but more specific) will help determine any structural abnormalities to the prostate. I would say, that further investigation would be wise at this point. I hope you find my response helpful sir. Please feel free to write back to me for any further clarifications, I would be more than happy to help you. Best wishes sir.