What Does It Mean When Alendronate Sodium Taken For Osteoporosis Inhibits Osteoclasts?

Posted on Wed, 12 Sep 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 12 Sep 2018 Answered on

Wed, 20 Apr 2022 Last reviewed on

Question : I recently began alendronate sodium for osteoporosis. I understand it inhibits osteoclasts. What doe it mean, I’d anything, that my serum C-telopeptide is decreasing.

Answered by Dr. Dr. Praveen Tayal (7 hours later)

Brief Answer:
It suggests alendronate is working well.

Detailed Answer:

Hello,

Osteoclasts are responsible for bone resorption and decreases the bone density. Alendronate sodium inhibits these cells and this decreases the bone resorption.
The decrease in levels of C-telopeptide indicates a decrease in bone resorption and suggests that alendronate is working correctly.

I hope this answers your query. In case you have additional questions or doubts, you can forward them to me, and I shall be glad to help you out. Wishing you good health.
Regards,
Dr. Praveen Tayal

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar