What Does My Biopsy Test Report Indicate?

Posted on Mon, 12 Sep 2016

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 12 Sep 2016 Answered on

Tue, 4 Oct 2016 Last reviewed on

Question : My mother in law Biopsy report says : Section show fibro collagenous cores of tissue with an infiltrating neoplasm composed of atypical cells with moderate degree of nuclear pleomorphism. Focal acinar pattern of arrangement seen. Normal appearing hepatocytes are seen in one of the crores.

what does it mean?

Answered by Dr. Indranil Ghosh (6 hours later)

Brief Answer:
appears to be a malignant tumor

Detailed Answer:
Hi
Thanks for your query.

As per this report it appears to be malignant, ie, cancerous. Apart from this nothing else can be commented as you have furnished no other information.

If you can get back to me with all the details, like patients's symptoms, scan reports, any other blood tests, etc, then I can guide you better.

Hope this helps.
Regards

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Indranil Ghosh (9 hours later)

Dear Dr

I have attached the blood test reports and MRI SCAN report.

The patient have the following symptoms

1. had jaundice, now she is almost cured

2. every night having heavy stomach pain also feeling heat on the stomach, after taking the pain killer, she is fine until next day night.

3. feeling tired.

4. Endorsescope done, all the result are normal.

5. Dr is saying unable to find the staring point of cancer.

6. She has removed the uterus 3 years back, any chance the cancer started from there?

Please advise doctor.

Best Regards

M.Arul

Answered by Dr. Indranil Ghosh (5 hours later)

Brief Answer:
Need to look at uterus biopsy

Detailed Answer:
Was the uterus biopsied? Then we need the report. If no cancer in that, then unlikely to be starting from there.

If no other source is found, we may have to treat it like unknown primary. Also immunohistochemistry tests can be done on current biopsy to give some idea.

Still, we may not find the primary and have to treat it anyway, with standard protocols for unknown primary.

Above answer was peer-reviewed by : Dr. Priyanka G Raj

Follow up: Dr. Indranil Ghosh (15 hours later)

Dear Dr

Thanks.

I will find the uterus biopsy report.

My question is, even the uterus removed 3 years, any chance for the cancer cell move from there to liver, and detected only now?

Now only symptom is stomach pain in night, can you please explain, is this because of cancer cell in liver or any other reasons?

BR

M.Arul

Answered by Dr. Indranil Ghosh (1 hour later)

Brief Answer:
Yes uterus to liver spread after 3 years is possible

Detailed Answer:
But I would keep that as a lower possibility.

This pain is most likely due to cancer cells in the liver.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Indranil Ghosh (5 hours later)

Dear Dr

Thanks for your prompt reply. In case unable to find the primary location and treat the cancer cells in the liver will be effective?

BR

M.Arul

Answered by Dr. Indranil Ghosh (33 minutes later)

Brief Answer:
it may still be effective

Detailed Answer:
Unfortunately this is incurable disease. But treatment based on unknown primary is often effective in temporarily slowing down the disease.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar