What Does My Wedge Biopsy Indicate?

Posted on Fri, 31 Oct 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Fri, 31 Oct 2014 Answered on

Tue, 25 Nov 2014 Last reviewed on

Question : SPECIMEN: WEDGE BIOPSY FROM HARD PALATE ULCER

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GROSS EXAMINATION: SINGLE MUCOSA COVERED TISSUE BIT MEASURING 1 X 0.8 X 0.5CM.

MICROSCOPIC EXAMINATION:STUDIED SERIAL SECTION SHOWS HYPERPLASTIC AND ACANTHOTIC STRATIFIED SQUAMOUS MUCOSA, SHOWING MODERATE TO SEVERE DYSPLASIA.

IN AREAS INVASION INTO SUBEPITHELIAL TISSUE IS NOTED.

Answered by Dr. Monish De (21 minutes later)

Brief Answer:
excision surgery followed by chemotherapy

Detailed Answer:
Hi

Since you are having hyperplastic and acanthotic stratified squamous mucosa showing moderate dysplasia and invasion in subepithelial tissue from hard palate ulcer you need an excision surgery followed by chemotherapy to kill the remaining cancer cells.

Regards
Dr De

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj