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What Does The FISH Result Of Fetus Indicate?

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Posted on Sat, 28 Feb 2015
Twitter Sat, 28 Feb 2015 Answered on
Twitter Fri, 20 Mar 2015 Last reviewed on
Question : In fish report result shows the following result, nuc ish 13q14 (LSi 13 x 2) 50 cells; nuc ish 21q22 (LSi 21x 2) 50 cells; nuc ish 18q14 (LSi 18 x 2) 50 cells; nuc ish {xp11.1-q 11.1 (CEP X) & nuc ish Y P11.1-q 11.1 (CEPY)} x 2 50 cells; 2 singles were seen for autosomes (13, 18 & 21) & sex chromosomes.
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Answered by Dr. Diptanshu Das (1 hour later)
Brief Answer:
Multiple genetic abnormalities present in FISH.

Detailed Answer:
Thanks for asking on HealthcareMagic.

I have carefully gone through the details. You have not indicated a number of details. I assume that this is the FISH result of an yet unborn fetus. I would require confirmation from you on this and if so, I need to know the gestational age of the fetus. The FISH results show number of genetic abnormalities and there is doubt whether it is actually viable for life.

I would request you to provide further details and let me know the things that you specifically want to know. I shall try to help you accordingly.

I would await your response.

Regards
Dr. Diptanshu Das
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Diptanshu Das (15 minutes later)
This is second trimester amniotic fluid test result sir...
doctor
Answered by Dr. Diptanshu Das (14 minutes later)
Brief Answer:
Outcome of pregnancy not favourable. Discuss the options with your doctor.

Detailed Answer:
Thanks for writing back.

I am sorry to let you know that the report is not quite favourable. There is doubt if the fetus will be viable. Even if I assume viability, major complications are likely. Please discuss with your doctor about the options. In such a scenario, you should perhaps consider medical termination of pregnancy.

For your information, you could go through the following:
http://contemporaryobgyn.modernmedicine.com/contemporary-obgyn/content/tags/abortion/options-second-trimester-termination?page=full
http://www.ncbi.nlm.nih.gov/pubmed/0000

Regards
Dr. Diptanshu Das
Note: For detailed guidance on genetic screening consult a genetics specialist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Diptanshu Das

Pediatrician

Practicing since :2005

Answered : 3879 Questions

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What Does The FISH Result Of Fetus Indicate?

Brief Answer: Multiple genetic abnormalities present in FISH. Detailed Answer: Thanks for asking on HealthcareMagic. I have carefully gone through the details. You have not indicated a number of details. I assume that this is the FISH result of an yet unborn fetus. I would require confirmation from you on this and if so, I need to know the gestational age of the fetus. The FISH results show number of genetic abnormalities and there is doubt whether it is actually viable for life. I would request you to provide further details and let me know the things that you specifically want to know. I shall try to help you accordingly. I would await your response. Regards Dr. Diptanshu Das