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What Does The Following MRI Report Indicate?

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Posted on Mon, 10 Nov 2014
Question: Can you please provide an interpretation in layman terms for an MRI report for an inoperable brainstem tumor. I writing out the current MRI report and the last report from April 2014. Can you please interpret the most recent and then compare to the last one? The original diagnosis was August 2002. Treatment at the Burzinski Clinic in XXXXXXX XXXXXXX in 2002-2004, radiation 2004. Recent treatment: July 2014 NDV, dendritic cell, hyperthermia, Vitamin C infusions, Taurolin.
This treatment was done in Vienna.

October 10, 2014 MRI
Stable to mild moderate cerebellar atrophy. No hydrocephalus, midline shift, or abnormal extra-axial fluid collections. No other focal brain parenchymal signal abnormalities. Major intracranial flow voids, orbits, mastoids unremarkable. Mild right maxillary sinus mucosal thickening. No abnormal brain parenchymal enhancement. Stable punctate focus of increased susceptibility right superior cerebellar hemisphere.

IMPRESSION:
Essentially stable MRI of the brain compared with 04/30/2014
Stable confluent abnormal increased T2 signal within the pons with associated mild expansion of the right anterior pons.
Stable mild to moderate cerebral atrophy.

April 2014 MRI Report

Reason For Exam: Malignant Neoplasm Brain
Examinations: MRI W/WO - (RMR/0006)-
History: Follow up brain tumor
Comparison: 03/25/13, 04/30/12, 05/17/10

Technique: Sagittal T1, axial PD/T2, axial DW-EPI, coronal Flair, axial T1 with gadolinium and coronal T1 with gadolinium.

FINDINGS: There is progressing confluent abnormal increased T2 signal within the pons bilaterally with increased expansion of the pons especially on the right anteriorly.

Ventricles and sulci are stable with persistent mild to moderate cerebellar atrophy.

There is a new small punctuate focus of increased susceptibility in the right superior cerebellar hemisphere, series 8, image 9. No other significant focal brain parenchymal signal abnormalities. Major intracranial flow void, orbits and paranasal sinuses unremarkable. Mild paranasal sinus mucosal thickening. No abnormal brain parenchymal enhancement.

IMPRESSION:
Increasing confluent T@ signal abnormality in the pons bilaterally with mild increased expansion of the pons especially on the right. No associated abnormal enhancement seen. Findings are concerning for tumor recurrence.

Mild to moderate cerebellar atrophy with new small punctate focus of increased susceptibility in the superior right cerebellar hemisphere, possibly a small cavernous angioma.

Mild paranasal sinus mucosal thickening.

No acute intracranial hemorrhage, infarct or hydrocephalus.
doctor
Answered by Dr. Monish De (48 minutes later)
Brief Answer:
recurrence

Detailed Answer:
Hi,

I went through the MRI report. With respect to your medical history, the following is my comment / explanation of the report:
Compared to the last mi brain report new abnormality findings are seen in the latest mi suggesting that the brain tumour has come back and has recurred and further treatment is necessary.

Regards
Dr de
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Monish De (21 minutes later)
I do not think that you understood my question. I realize that the April MRI showed the tumor growing again. However the October MRI stated it was stable. Please explain the findings in laymen terms of the MRI report. Also comment on the cerebellar atrophy.I would also like to ask what your recommended follow up treatment would be. The report states it is stable, if I am understanding that to mean there has been no further growth since April, then the treatment in Vienna was effective in stabilizing the tumor, correct?
doctor
Answered by Dr. Monish De (3 hours later)
Brief Answer:
Tumour under control

Detailed Answer:
Hi

Your last MRI brain report in october is showing stable disease meaning their is neither sufficient shrinkage of the tumour to qualify for partial response nor their is sufficient increase in size of tumour to qualify for progressive disease.

Their is also mild to moderate cerebral atrophy meaning their is loss of cells or shrinkage of brain.
When our brains atrophy, the neurons and their connections waste away and the brain is literally getting smaller.
You do not need to worry as the atrophy is stable and a small amount of brain atrophy is expected with age.

Follow up treatment would be to repeat a MRI of brain after 3 months.

Regards

DR De
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Ashwin Bhandari
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Answered by
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Dr. Monish De

Oncologist

Practicing since :2004

Answered : 2229 Questions

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What Does The Following MRI Report Indicate?

Brief Answer: recurrence Detailed Answer: Hi, I went through the MRI report. With respect to your medical history, the following is my comment / explanation of the report: Compared to the last mi brain report new abnormality findings are seen in the latest mi suggesting that the brain tumour has come back and has recurred and further treatment is necessary. Regards Dr de