What Does The Following Blood Test Report Indicate?

Posted on Wed, 23 Sep 2015

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Wed, 23 Sep 2015 Answered on

Fri, 9 Oct 2015 Last reviewed on

Question : Sir, I have done today my blood test for cbc and hiv test. Hiv test shows result non-reactive where as cbc shows wbc of 4000/cmm and platelets count of 127000/cmm and megaplatelets are seen on smear. Sir, is this all normal. I have attached reports also.

Answered by Dr. Indu Kumar (27 minutes later)

Brief Answer:
Mega platelets may be due to vitamin B12 or folate deficiency.

Detailed Answer:
Hello

Sometimes mega platelets can cause false low platelet count as large platelets may not be counted by machine.
So,you may need peripheral smear count.If peripheral smear platelet count is still low,then it may be due to vitamin B12 or folate deficiency.You may need assessment of these factors.
If it is ruled out then few disorders related to excess platelet destruction or reduced platelet production should be considered.
Bone marrow examination can be done if needed.

It is good that other factors related to blood are normal.
You may need evaluation by a hematologist.

WBC count is towards lower limit and it is not concerning.
It is good that HIV tests are negative.

Get well soon.
Hope I have answered your question.
Further queries are most welcome.

Take Care
Dr.Indu XXXXXXX

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

Follow up: Dr. Indu Kumar (39 minutes later)

Sir, I have a doubt that my wbc counts are low and this could be due to hiv. Sir, do I need to do the test again. The hiv test they have done is of cmia type which they say is pretty accurate. And I had unprotected sex about six months ago. Sir, what do you suggest.

Answered by Dr. Indu Kumar (2 hours later)

Brief Answer:
There are almost no chance of false negative HIV report.

Detailed Answer:
Hello

There are almost no chance of false negative HIV report.Tests are highly sensitive and specific.
As you had exposure 6 months back,tests must been positive if you have had the disease.After 12 weeks,tests are highly specific.
I don't think you need repeat test.You are almost safe.

WBC count is not low.It is only towards lower limit.It can be considered as normal.

Get well soon.
Hope I have answered your question.
Further queries are most welcome.

Take Care
Dr.Indu XXXXXXX

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar