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What Does This CA Values Regarding Ovarian Cyst Indicate?

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Posted on Tue, 5 Aug 2014
Question: Hi. I have an ovarian cyst & have recently had several blood tests. CA19.9 & CA125 have both come back 'high'. I have been scheduled to have an abdominal & pelvic ultrasound & CT scan next week. What do these blood results really mean.
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Answered by Dr. Shanti Vennam (44 minutes later)
Brief Answer:
They are tumor markers.

Detailed Answer:
Hi,

Thanks for writing to us.

CA 19.9 and CA 125 are tumor markers. While CA 125 is used to test for a wide variety of tumors, its most important use is in the diagnosis of an ovarian malignancy. The normal value is less than 35 U/ml.

Together, CA 19.9 and CA 125 are used to differentiate a mature cystic teratoma from an ovarian cancer. Simultaneous elevation of both has been shown to be associated with a higher probability of malignancy.

Endometriosis may also be sometimes detected through this test, though the benefits are to be further evaluated.

Since you have an ovarian cyst, these findings suggest the possibility of a malignancy; yet, a definite conclusion can be arrived at only after the CT and the sonogram.

Hope your query has been clarified. Please feel free to contact for any more information. I will be happy to help.

regards,
Shanti.V.
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shanti Vennam

OBGYN

Practicing since :1989

Answered : 7667 Questions

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What Does This CA Values Regarding Ovarian Cyst Indicate?

Brief Answer: They are tumor markers. Detailed Answer: Hi, Thanks for writing to us. CA 19.9 and CA 125 are tumor markers. While CA 125 is used to test for a wide variety of tumors, its most important use is in the diagnosis of an ovarian malignancy. The normal value is less than 35 U/ml. Together, CA 19.9 and CA 125 are used to differentiate a mature cystic teratoma from an ovarian cancer. Simultaneous elevation of both has been shown to be associated with a higher probability of malignancy. Endometriosis may also be sometimes detected through this test, though the benefits are to be further evaluated. Since you have an ovarian cyst, these findings suggest the possibility of a malignancy; yet, a definite conclusion can be arrived at only after the CT and the sonogram. Hope your query has been clarified. Please feel free to contact for any more information. I will be happy to help. regards, Shanti.V.