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What Does This Biopsy Report For Breast Cancer Indicate?
Question: hi Dr.
i have breast cancer dcis. My path report for the tumour says - invasive carcinoma - present.
'Tumour Focality: single focus of microinvasive carcinoma.
The overall grading, tumubar formlation and pleomorphism were not graded because it's microinvasion.
what is the significance of this? Does this play a role in my overall post mastectomy treatment ?
thank you
i have breast cancer dcis. My path report for the tumour says - invasive carcinoma - present.
'Tumour Focality: single focus of microinvasive carcinoma.
The overall grading, tumubar formlation and pleomorphism were not graded because it's microinvasion.
what is the significance of this? Does this play a role in my overall post mastectomy treatment ?
thank you
Brief Answer:
No treatment has been completed
Detailed Answer:
Hi
Thanks for your query.
As it is predominantly DCIS and only single focus of microinvasion (minute invasion) is present, and complete mastectomy has been done, there is no role for any future radiotherapy or chemotherapy.
However, if the tumor is hormone receptor positive, we can consider hormone therapy (oral tablets) but it is mainly for risk reduction of future breast cancer or DCIS.
Hope this helps.
Regards
No treatment has been completed
Detailed Answer:
Hi
Thanks for your query.
As it is predominantly DCIS and only single focus of microinvasion (minute invasion) is present, and complete mastectomy has been done, there is no role for any future radiotherapy or chemotherapy.
However, if the tumor is hormone receptor positive, we can consider hormone therapy (oral tablets) but it is mainly for risk reduction of future breast cancer or DCIS.
Hope this helps.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Brief Answer:
grade of DCIS doesn't influence post-mastectomy treatment
Detailed Answer:
In lymph nodes it is not called microinvasion but either isolated tumor cells or micrometastases. Which one did you have ?
isolated cells are treated as node negative and hence no adjuvant. If micrometastases, then treatment discussed (not necessarily given).
grade of DCIS doesn't influence post-mastectomy treatment
Detailed Answer:
In lymph nodes it is not called microinvasion but either isolated tumor cells or micrometastases. Which one did you have ?
isolated cells are treated as node negative and hence no adjuvant. If micrometastases, then treatment discussed (not necessarily given).
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
thank you. So there is no risk that i can also get breast cancer on the other breast in the next 5 years? i had mastectomy on my left breast. My right breast was diagnosed as having PASH
Brief Answer:
yes, risk will be there
Detailed Answer:
Even somebody who did not have breast Cancer also has got some risk so for you it is slightly higher than that. Maybe 10-20% more than a normal person. You can discuss with your oncologist regarding risk reduction hormonal therapy for that. But this is not for preventing relapse of this cancer/dcis.
PASH is benign.
yes, risk will be there
Detailed Answer:
Even somebody who did not have breast Cancer also has got some risk so for you it is slightly higher than that. Maybe 10-20% more than a normal person. You can discuss with your oncologist regarding risk reduction hormonal therapy for that. But this is not for preventing relapse of this cancer/dcis.
PASH is benign.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
hi Dr. XXXXXXX
if you have isolated tumour cells in 1 lymph node (4 were removed during mastectomy), how do you know if there are not more tumour cells in the other lymph nodes or in your blood (without doing a blood test)? Does it matter if my dcis was microinvasive, grade 3 with extensive necrosis?
if you have isolated tumour cells in 1 lymph node (4 were removed during mastectomy), how do you know if there are not more tumour cells in the other lymph nodes or in your blood (without doing a blood test)? Does it matter if my dcis was microinvasive, grade 3 with extensive necrosis?
Brief Answer:
That doubt will remain
Detailed Answer:
Were this nodes removed as sentinel nodes or a complete dissection performed? If complete dissection was performed then this number is bit low. But on the other hand, for DCIS node dissection is not required, for microinvasive cancer it is, at least a sentinel node.
Blood tests don't help in this scenario. They are much less sensitive to detect a few tumor cells.
The grade and histological features will not matter as a mastectomy has been done. If it was breast conservation, then it would have.
That doubt will remain
Detailed Answer:
Were this nodes removed as sentinel nodes or a complete dissection performed? If complete dissection was performed then this number is bit low. But on the other hand, for DCIS node dissection is not required, for microinvasive cancer it is, at least a sentinel node.
Blood tests don't help in this scenario. They are much less sensitive to detect a few tumor cells.
The grade and histological features will not matter as a mastectomy has been done. If it was breast conservation, then it would have.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
the nodes were removed as sentinel during surgery. So there is no way to know if i have tumour cells in either my blood or other nodes other than wait and see correct? thank you again
Brief Answer:
Then it is fine
Detailed Answer:
If this is after sentinel node then possibility of you harbouring cancer cells in any other lymph node is extremely low. And blood tests are not reliable at all.
So I guess it is just follow up. Chances of recurrence are bare minimum in my opinion.
Regards
Then it is fine
Detailed Answer:
If this is after sentinel node then possibility of you harbouring cancer cells in any other lymph node is extremely low. And blood tests are not reliable at all.
So I guess it is just follow up. Chances of recurrence are bare minimum in my opinion.
Regards
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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