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What Does This Lab Report Indicate?

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Posted on Wed, 2 Nov 2016
Question: For the below test

HBsAg(Hepatitis B Surface Antigen)
Method :ECLIA Specimen: SERUM

The lab gave result as REACTIVE (5823.0).

What does this means? Is this a very high value? Do I need to take any medication?
doctor
Answered by Dr. Tushar Kanti Biswas (9 hours later)
Brief Answer:
HBsAg positive state

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.

You are positive for HBsAg (Hepatitis B Surface Antigen).
To determine whether you are having active infection or chronic infection or an inactive carrier state,you have to undergo the following tests for serologic and virologic markers:
Anti-HBs
Anti-HBc
Anti-HBe
HBeAg

Positive HBsAg and Anti-HBs indicate carrier state.
Positive HBsAg, IgM anti-HBc indicate acute infection(Acute Viral Hepatitis B )
Positive HBsAg and IgG anti-HBc indicate Chronic infection(Chronic Viral Hepatitis B ).In such case HBeAg , a marker of replication and HBV DNA load are estimated.

HBeAg is a qualitative marker and HBV DNA a quantitative marker of this replicative phase.
The concentration of HBsAg > 500 μg/mL is high but significance of this high value can be determined by the above additional tests.
You need to undergo also Liver function test like serum blirubin,SGOT(Serum glutamic oxaloacetic transaminase) and SGPT (serum glutamic-pyruvic transaminase)

Regards

Dr. T.K. Biswas M.D. XXXXXXX

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Tushar Kanti Biswas

Internal Medicine Specialist

Practicing since :1975

Answered : 1920 Questions

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What Does This Lab Report Indicate?

Brief Answer: HBsAg positive state Detailed Answer: Hi, Thank you for your query. I can understand your concerns. You are positive for HBsAg (Hepatitis B Surface Antigen). To determine whether you are having active infection or chronic infection or an inactive carrier state,you have to undergo the following tests for serologic and virologic markers: Anti-HBs Anti-HBc Anti-HBe HBeAg Positive HBsAg and Anti-HBs indicate carrier state. Positive HBsAg, IgM anti-HBc indicate acute infection(Acute Viral Hepatitis B ) Positive HBsAg and IgG anti-HBc indicate Chronic infection(Chronic Viral Hepatitis B ).In such case HBeAg , a marker of replication and HBV DNA load are estimated. HBeAg is a qualitative marker and HBV DNA a quantitative marker of this replicative phase. The concentration of HBsAg > 500 μg/mL is high but significance of this high value can be determined by the above additional tests. You need to undergo also Liver function test like serum blirubin,SGOT(Serum glutamic oxaloacetic transaminase) and SGPT (serum glutamic-pyruvic transaminase) Regards Dr. T.K. Biswas M.D. XXXXXXX