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What Does This Liver Function Test Result In A Person With History Of Hepatitis B Indicate?

Posted on Wed, 12 Aug 2015

Question: sir,presently my son age is 31, when he was 17 (2001) hepatitis b diagnosed.
HBs Ag + ve
anti HBc IgM +ve
HBe Ag - ve . Other results are as (2012 ):
alkaline phosphatase 88
GGT 34
SGPT 28
SGOT 29
PROTIN -total 8
albumin-serum 4.72
Presently there is no health problem/ treatment,pl advise me if any test or treatment needed.
Thanks
XXXX

Answered by Dr. Prashant (1 hour later)

Brief Answer:
Only HBV DNA,LIVER FUNCTION TEST AND ULTRASOUND ABDOMEN ONCE IN 6 MONTHS

Detailed Answer:
HI,
He is been diagnosed hepatitis B in 2001 and till now his liver enzymes are normal no ALT elevation or low albumin ,Now you can consider couple of blood tests like HBV DNA (Quantitative) ,Liver function test and an ultrasound abdomen to know the liver status and a gastroscopy to rule out esophageal varices .
If every thing is normal then no need to worry just regular follow up every 6 months with HBV DNA, LFT and USG abdomen is enough.
If any abnormality then please kindly consult a gastroenterologist for further management.
Hope this information help you
Thank you.

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Prashant (48 hours later)

sir,if he take a chance for children, then what precautionary treatment will needed in both the cases when spouse is vaccinated or not vaccinated.
In 2001results of Gasroscopy report are as
esophagus normal /no vx

stomach no fundal vx
fundus
body no clp
antrum pylorus normal
duodenum normal
Results of upper abdominal sonoscan are as
Liver : shows mild hepatomegaly with altered homogenous echotexture of the liver parenchyma in both lobes of liver.
no localised solid or cystic area is noted.
no sign of billiary obstruction are noted.
no free fluid is noted.
GB: SHOWS NORMAL findings.
cbd is within normal limits.
PANCREAS: normal shape,size and echotexture.
SPLEEN: shows border line spleenomegaly with homogenous echotexture.
SUMMARY: ABOVE FINDINGS ARE indicative for mild hepato-spleenomegaly with possible changes of hepatitis needs correlation with clinico pathological findings.
Thanks

Answered by Dr. Prashant (1 hour later)

Brief Answer:
There is almost negligible chance of seminal transformation to wife

Detailed Answer:
hi,
your son can actually plan for children ,there is negligible chances of virus transformation from semen,only precaution is if wife is not vaccinated get a vaccination done to her to be on safer side.
And regarding gastroscopy 2001 is normal but he need to get repeat gastroscopy for screening for varix again and get all other investigation which i asked above for further management
Thank you

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Prashant (45 hours later)

Sir,
I agree with you ,but i want to tell you that at that time (2002) myself and my wife also go for hepatitis b test and diagnosed positive this means that virus of hepatitis was transfer from we to our son.
Thanks.

Answered by Dr. Prashant (20 minutes later)

Brief Answer:
From mother to child there are high chances of transferring

Detailed Answer:
Exactly the virus might have transferred from mother but there are really less chances from father to mother ,so I advised in my last reply for complete vaccination to wife ,so that the chances will be negligible .
And regular follow up with your doctor.
thank you

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Above answer was peer-reviewed by : Dr. Shanthi.E