What Dosage Of Bupropion Is Severely Damaging Or Potentially Fatal?

Posted on Mon, 3 Aug 2015

Question: Can you please tell me at what doses of buproprion SR 150mg, does the medication become severely damaging or potentially fatal? I am aware of the risk of seizure.

Answered by Dr. Dr. Muhammad Sareer Khalil (13 minutes later)

Brief Answer:
not more than 450 mg / day , consult your doctor before taking medication

Detailed Answer:
Hello and Welcome

I appreciate your concern

Any dose of bupropion above 450 mg per day can cause significant side effects. the potential for seizure is also twice as likely with a dose above 450 mg. Severity and unpredictability of adverse effects increases with higher doses.

Wishing you best of health

Thanks

Please consult your doctor before taking any medication.

For future follow up / correspondence you may ask me directly at the link given below

http://doctor.healthcaremagic.com/Funnel?page=askDoctorDirectly&docId=68107

Dr. M.S. Khalil

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Muhammad Sareer Khalil (21 minutes later)

What would the follow up care to a Wellbutrin OD induced grand mal seizure be? Is the protocol to throw the individual into a psychiatric hospital or would they stay under medical care for some (24+ hours) period of time?

Answered by Dr. Dr. Muhammad Sareer Khalil (5 hours later)

Brief Answer:
Explained

Detailed Answer:
Hello.

Treating the seizure e.g via divalproex sodium after securing airway , breathing and circulation, Limiting further absorption, neutralizing any remaining drug in GIT if appropriate via adsorbents should be done. No, the patient can not be shifted to a psychiatric hospital until the seizures have subsided and the patient is in a more stable condition.

Wishing you best of health

Thanks

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar