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What Is Subcapsular Hypodense Liver Metastasis?

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Posted on Sat, 28 Mar 2015
Question: What is subcapsular hypodense liver metastaes in a colon cancer pt? Is this liver or peritonial area ?
doctor
Answered by Dr. Monish De (53 minutes later)
Brief Answer:
Small area in the liver.

Detailed Answer:
Hi

Subcapsular hypodense liver metastasis is a small area in the liver.

It is not in the peritoneal area.

The colon cancer has now spread to the liver region and is in stage 4.

Treatment option at this stage is palliative chemotherapy.

Regards

DR DE
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Monish De (37 minutes later)
I attach a image. What do you see on it? We r confussed as this was in january and we were told theres 2 livee mets only .

2013
A mri comfirmed simple liver cysts.

Also u will see on ct report radiologist mentions
No peritoneal disease right? But incologost says poss peritoneal
Disease . We r confussed.

Does image show peritoneal ?

Also will chemo work? And sirt therapy?

If it does work then can survival be good?
doctor
Answered by Dr. Monish De (10 minutes later)
Brief Answer:
Average survival around 5 years.

Detailed Answer:
Hi


I have gone through the reports.

The disease has now progressed and the liver lesions has increased in size.

CT image does not show peritoneal disease.

Selective internal radiation therapy (SIRT) therapy is still under trial and will not work.

Palliative chemotherapy will work.

If the chemotherapy works then survival will be good and it will be around 5 years.

Regards

DR DE

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Monish De (1 hour later)
Does chemotherapy usually work ?

Which is best one?

In uk sirt is approved and used. Should we go for that with chemo?

If
Chemo fails r there other options

?
doctor
Answered by Dr. Monish De (19 minutes later)
Brief Answer:
RFA and Cryosurgery

Detailed Answer:
Hi

Chemotherapy usually works.

Since FOLFIRI chemotherapy has already been used as per the history of the CT scan report i would advise you to try second line chemotherapy with Regorafenib.

I will advise you to use SIRT in conjunction with chemotherapy and combined modality of treatment produces response rate of about 85%.

If chemotherapy fails then Radiofrequency ablation (RFA) is another option.

This method uses a high frequency electrical current to destroy cancer cells.

RFA delivers an electrical current to the liver metastasis through a thin probe, which is inserted through the skin and may be guided to the tumour by ultrasound or a CT scan.

The probe is inserted into the tumour and very thin prongs are extended deeper into the tumour. The prongs deliver the electrical current, which heats up the tumour tissue and destroys the cancer cells.

RFA can be given through the skin, a surgical incision in the abdomen or a laparoscope. RFA is usually well tolerated and can be repeated several times if needed.

One more option is Cryosurgery.

This method destroys abnormal cells or tissues by freezing them.

Cryosurgery delivers an extremely cold liquid or gas to the tissues of the liver through a metal tube called a cryoprobe.


The cryoprobe may be guided to the liver metastases by ultrasound. The area is allowed to thaw and then is frozen again.

The freezethaw cycle may need to be repeated a few times.

Cryosurgery may be done through a surgical incision in the abdomen or sometimes it can be done through a laparoscope.

If you have no more clarifications then please rate the answer and close the thread.

Regards

DR DE



Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Monish De (14 minutes later)
Thx so much. But 1 liver met is 7 cm so can crysuregry work ?

Also
Would
Sirt and chemo improve survival?

Finally, how many lesions do you see and could
Any be cysts as he also has a history of simple liver cysts
Or could the cysts have disappeared?
doctor
Answered by Dr. Monish De (6 minutes later)
Brief Answer:
SIRT and chemotherapy will improve survival by 2 years.

Detailed Answer:
Hi

As one liver mets is 7 cm RFA is better option if chemotherapy fails rather than cryosurgery.

SIRT and chemotherapy will improve survival by 2 years.

There are atleast 2 liver metastasis present and these are not liver cyst.

The liver cysts have disappeared.

Regards

DR DE


Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Monish De (47 minutes later)
Thanks. Could survival extend
To 5 years with chemo
And sirt ?!

Does
Chemotherapy tend
To work in ppl?
doctor
Answered by Dr. Monish De (13 minutes later)
Brief Answer:
Extend survival by more than 5 years.

Detailed Answer:
Hi

90% of metastatic colon cancer patients treated with combined modality treatment of chemotherapy and SIRT will extend survival by more than 5 years.

Chemotherapy works in people and provide response rate of 85%.

Regards

DR DE
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
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Follow up: Dr. Monish De (14 minutes later)
Last query, sorry, what if chemo
Fails
Again. We r worried that as 1 did not work, all
Wont work?

We are stuck then right?
doctor
Answered by Dr. Monish De (5 minutes later)
Brief Answer:
Regorafenib chemotherapy has a response rate of 80%.

Detailed Answer:
Hi

It is not necessary that second line chemotherapy will also not work as one line has already failed.

Regorafenib chemotherapy has a response rate of 80%.

If chemotherapy fails then RFA can be tried and it has a response rate of 75% and will extend overall survival by 2 years.

So everything is not lost.

Wishing you good health.

Regards

DR DE

Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
Answered by
Dr.
Dr. Monish De

Oncologist

Practicing since :2004

Answered : 2229 Questions

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What Is Subcapsular Hypodense Liver Metastasis?

Brief Answer: Small area in the liver. Detailed Answer: Hi Subcapsular hypodense liver metastasis is a small area in the liver. It is not in the peritoneal area. The colon cancer has now spread to the liver region and is in stage 4. Treatment option at this stage is palliative chemotherapy. Regards DR DE