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What Is The Most Effective Medication For The Treatment Of Gout?

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Posted on Mon, 12 Dec 2016
Question: What is currently the most effective drug for the treatment of gout?
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Answered by Dr. Michelle Gibson James (19 minutes later)
Brief Answer:
Add an NSAID to the colchicine, if can't use NSAIDs, may need steroids

Detailed Answer:
HI, thanks for using healthcare magic

Gout is managed in 3 stages: (1)treating an acute attack of pain/swelling etc
(2)providing medications to prevent flare ups
(3)lowering the excess stores of urate to prevent these flares

Treatment of an acute attack can involve NSAIDS (ibuprofen,naproxen, voltaren, indomethacin), steroids, colchicine , ACTH.

The NSAIDs are most often started during an acute flare up unless there is a reason they can't be used (Eg if you have stomach problems such as an ulcer, bleeding or severe liver or kidney disease).
They are normally given at full strength for 2 to 5 days

Colchicine is not used as often now because it has a narrow therapeutic window, this means a slight change in dose can cause bad side effects

Steroids are given to persons who cannot use the NSAIDs. May be given by tablet, intramuscular injection, iv injection or into the joint.

Medication is not started to lower the levels of uric acid during an acute attack/flare up , because this can intensify and prolong it.

I hope this helps, feel free to ask any other questions
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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What Is The Most Effective Medication For The Treatment Of Gout?

Brief Answer: Add an NSAID to the colchicine, if can't use NSAIDs, may need steroids Detailed Answer: HI, thanks for using healthcare magic Gout is managed in 3 stages: (1)treating an acute attack of pain/swelling etc (2)providing medications to prevent flare ups (3)lowering the excess stores of urate to prevent these flares Treatment of an acute attack can involve NSAIDS (ibuprofen,naproxen, voltaren, indomethacin), steroids, colchicine , ACTH. The NSAIDs are most often started during an acute flare up unless there is a reason they can't be used (Eg if you have stomach problems such as an ulcer, bleeding or severe liver or kidney disease). They are normally given at full strength for 2 to 5 days Colchicine is not used as often now because it has a narrow therapeutic window, this means a slight change in dose can cause bad side effects Steroids are given to persons who cannot use the NSAIDs. May be given by tablet, intramuscular injection, iv injection or into the joint. Medication is not started to lower the levels of uric acid during an acute attack/flare up , because this can intensify and prolong it. I hope this helps, feel free to ask any other questions