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Which All Medicines Are Best Avoided During Pregnancy?

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Posted on Wed, 15 Oct 2014
Question: Doctor! my age is 26yrs,i am pregnant,this is my first month of pregnancy.
i want to know which medicines are prohibited during pregnancy in first trimester and which should be taken during this. can i take ENO if i feel gastric problem?
doctor
Answered by Dr. Vivek Chail (14 minutes later)
Brief Answer:
Eno when required but not more than once in a day

Detailed Answer:
Hi XXXX,
Thanks for writing in to us.

I have read through your query in detail.
Eno can be taken during pregnancy but only when required and not more than once in a day. There are many medicines which can cause variable risk to fetus during pregnancy. Some medicines are given with caution after evaluating risk and benefit. Giving you complete list of such medicines is difficult,however you may like to ask should you be taking any particular medicine.

There is categorization of medicines for use in pregnancy followed by FDA.

Category A
Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Category N
FDA has not classified the drug.

Hope your query is answered.
Please write back if you have any doubts.

Regards,
Dr.Vivek

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Vivek Chail (2 days later)
doctor! some of the medicine used very common in our day to day life ,i listed them below and i want your advice on them for use in any time/month/trimester of pregnancy. i am very cautious about medicine specially in pregnancy.
medicine about like:--
(ibuprofen,paracetamol,nimsulide,dicyclomine)-painkiller
(pseudoephiderine,chlorpheniramine,ambroxol,cetrizine,terbutaline,dexomethorfen)-cold/cough
(follic acid,iron,ferrus ascorbate,ferrus sulfate),sodium bi carbonate,multivitamine-tonic
(fexofindine,pheniramine melate,motelucast)-allergy
(cephalosporine antibiotics,azithromycine,quinolones)-for infections
Thanks&Regards
doctor
Answered by Dr. Vivek Chail (56 minutes later)
Brief Answer:
Please find details below

Detailed Answer:
Hi XXXX,
Thanks for writing back with an update.

Please find the category of the drug mentioned with the name.
1. ibuprofen should be given when potential benefits may warrant use of the drug in pregnant women despite potential risks
2. paracetamol can be given during pregnancy
3. nimesulide should never be used in pergnancy
4. dicyclomine should be used during pregnancy only if clearly needed.
5. Pseudoephedrine is only recommended for use during pregnancy when benefit outweighs risk.
6. Chlorpheniramine is only recommended for use during pregnancy when benefit outweighs risk.
7. Ambroxol is advisable to avoid use during the first trimester of pregnancy.
8. cetrizine should be used during pregnancy only if clearly needed.
9. Terbutaline is only recommended for use during pregnancy when benefit outweighs risk.
10. Dextromethorphan should be given only if the potential benefit justifies the potential risk to the foetus.
11. Folic acid the recommended daily allowance of folic acid during pregnancy is 400 to 800 mcg/day.
12. Ferrous ascorbate and ferrous sulfate can be given during pregnancy.
13. sodium bi carbonate,multivitamine-tonic can be given during pregnancy
14. fexofenadine should be given only if the potential benefit justifies the potential risk to the foetus.
15. pheniramine melate should be given only if the potential benefit justifies the potential risk to the foetus.
16. montelukast failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
17. cephalosporin The drug group is generally considered safe for use during pregnancy, but each drug is slightly different and may have different side effects
18. azithromycin failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
19. quinolones are contraindicated except for when no other safe alternative antibiotic exists.

Hope your query is answered.
Please write back if you have any doubts.

Regards,
Dr.Vivek
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
Answered by
Dr.
Dr. Vivek Chail

Radiologist

Practicing since :2002

Answered : 6874 Questions

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Which All Medicines Are Best Avoided During Pregnancy?

Brief Answer: Eno when required but not more than once in a day Detailed Answer: Hi XXXX, Thanks for writing in to us. I have read through your query in detail. Eno can be taken during pregnancy but only when required and not more than once in a day. There are many medicines which can cause variable risk to fetus during pregnancy. Some medicines are given with caution after evaluating risk and benefit. Giving you complete list of such medicines is difficult,however you may like to ask should you be taking any particular medicine. There is categorization of medicines for use in pregnancy followed by FDA. Category A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). Category B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. Category C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Category D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Category X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits. Category N FDA has not classified the drug. Hope your query is answered. Please write back if you have any doubts. Regards, Dr.Vivek