Which Alternative Drug Can Act As The Best Replacement Drug For Zoloft When Diagnosed With Depression?

Posted on Sun, 4 Feb 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 4 Feb 2018 Answered on

Wed, 22 Aug 2018 Last reviewed on

Question : I have successfully been on Zoloft for over 25 years. In my early 80's I am up to XXXXXXX dosage. Zoloft does not seem to be working as it did in the past. If you were to recommend another anti-depressant as a replacement what would it be?

Answered by Dr. Dr. Soujanya (16 minutes later)

Brief Answer:
Fluoxetine would be better.

Detailed Answer:
Hi sir,

I have gone through your query and understand your concern towards the nonresponsive of Zoloft, after many years.

I would suggest you can switch off to MIRTAZAPINE, which improves your sleep and appetite in addition with safest side effect profile.

It is a good antidepressant in action.

Consult with your doctor about this drug.
Hope this information would help you.
Thank you.
Dr. Soujanya

Above answer was peer-reviewed by : Dr. Yogesh D