
Why Are Herpain Shots Prescribed For Conception?



FET done on 10th Aug, and pregnancy confirmed on 29th Aug with ultrasound scan of gestational sac of 2.67 mm which i had already discussed in previous queries to you. But not sure if that history would be available while addressing this query.
now , the question about the medication am going through currently.
At the time of transfer , thyroid levels are detected as 8 (guess it is wrong lab report a i never miss taking medicine) , so , instantly, doctor suggested to take 75 mg dose from that day. I have repeated the test just a week after and thyriod levels are in normal range of 3. Though , am telling to doctor that it came down with latest report , they didn't considered that and increased another 25mg dose post pregnancy confirmation. normally, for all others , they are increasing 25mg post successful pregnancy. in my case, i think it supposed to be 50mg + 25 mg. Rather , 100 mg is mentioned in the prescription. and hardly, we never get chance to talk to main doctor, she does only scan , and prescriptions would be printed out and explained by junior doctors. and they never be in a mood of listening to patient concerns. leaving that apart, what is the right dosage of thyronorm now?
And, my infertility hospital has tie up with outside general physician who prescribed to take Cutenox 40 mg injection (LMWH treatment) from the time of embroy transfer date as long as platelet count does not drop to 1.5L
First thing, they never explained properly how does it help pregnancy? and frequency of that injection is daily which is very very painful too.
And platelet count must be tested for every 5-7 days. my PLC count was 405000 cumm when i started taking this injection. by today , it went up to 430000 cumm which is above the normal range. am worried about side effects of it if it goes up ...
and could not understand whether to continue this injection or not? infertility hospital is irresponsible in answering this as they are not pretty much sure about it.
And when am trying to contact the general physician who suggested to take this injection, he is not responding now. planning to meet in person but his availability is really really difficult.
I need to understand ,
1. what is an important role does this injection play in supporting pregnancy through ICSI +FET procedure.
2. How long i should continue taking this injection? if my platelet never drops below 1.5L , should i be taking till the end of pregnancy? PLC > 430000 - does it have any impact on pregnancy?
3. What if i stop taking this injection ? or reduce the frequency of taking it?
4. does it have any relation with TNF / NK ? i had gone through endometrial biopsy 2 years ago and identified TB and given medication for 8 months , i did completed the course. After an year , i went through ICSI Cycle.
5. am having intralipid every month saying that helps in killing NK cells. Happened on the day of transfer , and again on the day of confirmation of pregnancy. does it really needed?
Sorry, so many questions flowing in my mind as my fertility hospital is unable to give any answers. each time a new doctor will be seen and they just explain the printed prescription. As success rates are more, we are proceeding there and continuing whatever it is.
You can stop Intralipid and LMWH
Detailed Answer:
Hi,
Good to see you back.
Following is my reply :
1) Low molecular weight heparin injections are supposed to counter any unknown factors like antiphosppholipid antibodies and other factors which form clots in microcirculation and lead to miscarriages.
2) These are prophylactic injections and needed only as prevention of possible miscarriage.
3) These injections are not compulsory and can be stopped if you are uncomfortable with them.
4) Platelet counts need not be repeated if there are no fluctuations till now. You can do it once a month only.
5) Intralipid has no evidence in literature. It's not required. NK cell activity or TNF are not a factor to worry about.
6) Continue thyroid as per prescription. Repeat TSH and let me know.

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