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Why Is Triple Marker Screening Test Prescribed During Pregnancy?

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Posted on Tue, 30 Jun 2015
Question: Can you please let me know the details of Triple Marker screening test for pregnants? On what conditions this test is to be prescribed?

Regards,
XXXX
doctor
Answered by Dr. Shanthi E (2 hours later)
Brief Answer:
Triple Marker screening test elaborated

Detailed Answer:
Hi XXXX,

I have read your query.

Triple Marker screening test is a blood test that is offered for all pregnant women. However, it is highly recommended for pregnant women who have family history of birth defects, who are older than 35 years of age, who other other co-morbid medical conditions such as Diabetes.

The test involves measuring the blood or serum levels of alpha-fetoprotein (AFP), unconjugated estriol (UE3), and human chorionic gonadotropin (beta-hCG).

Pregnancies are classified as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects) based on this test.

The test is done primarily to rule out chromosomal abnormalities such as Down's syndrome, Edward's syndrome and neural tube defects such as spina bifida.

I would like to explain this in simple terms to you. Do let me know if something is not clear to you.

Regards,
Above answer was peer-reviewed by : Dr. Prasad
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Answered by
Dr.
Dr. Shanthi E

General & Family Physician

Practicing since :2005

Answered : 2483 Questions

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Why Is Triple Marker Screening Test Prescribed During Pregnancy?

Brief Answer: Triple Marker screening test elaborated Detailed Answer: Hi XXXX, I have read your query. Triple Marker screening test is a blood test that is offered for all pregnant women. However, it is highly recommended for pregnant women who have family history of birth defects, who are older than 35 years of age, who other other co-morbid medical conditions such as Diabetes. The test involves measuring the blood or serum levels of alpha-fetoprotein (AFP), unconjugated estriol (UE3), and human chorionic gonadotropin (beta-hCG). Pregnancies are classified as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects) based on this test. The test is done primarily to rule out chromosomal abnormalities such as Down's syndrome, Edward's syndrome and neural tube defects such as spina bifida. I would like to explain this in simple terms to you. Do let me know if something is not clear to you. Regards,