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Will It Help To Increase Methadone Dosage While Introducing Tegretol To The Medication Dosage?

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Posted on Wed, 15 Aug 2018
Twitter Wed, 15 Aug 2018 Answered on
Twitter Sat, 26 Mar 2022 Last reviewed on
Question : Hi, will it help to increase methadone dosage if introducing tegrtol to meds?
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Answered by Dr. Seikhoo Bishnoi (1 hour later)
Brief Answer:
Tagretol might reduce the Methadone levels.

Detailed Answer:

Hello,

Tagretol is Carbamazepine. Carbamazepine is an hepatic enzyme inducer. The drug if used with Methadone results in increased metabolism of Methadone and is known to lower the Methadone levels.

So introducing Tagretol to medicines should reduce the Methadone levels and thus Methadone dose should be increased to get desired effects.

Please don't hesitate to ask again for more clarifications.
Thanks.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Seikhoo Bishnoi

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Practicing since :2007

Answered : 5192 Questions

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Will It Help To Increase Methadone Dosage While Introducing Tegretol To The Medication Dosage?

Brief Answer: Tagretol might reduce the Methadone levels. Detailed Answer: Hello, Tagretol is Carbamazepine. Carbamazepine is an hepatic enzyme inducer. The drug if used with Methadone results in increased metabolism of Methadone and is known to lower the Methadone levels. So introducing Tagretol to medicines should reduce the Methadone levels and thus Methadone dose should be increased to get desired effects. Please don't hesitate to ask again for more clarifications. Thanks.