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Will Rubella Positive With High Avidity Cause Problems In Pregnancy?

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Posted on Mon, 10 Aug 2015
Question: Hallo doc...I had my last periods on 26th iapril. 2015.n now m 3 months 24 days pregnant dat is confirmed...in d starting of my 3 rd month my doctor asked me to go for rubella IGg test ...dat ws found wid a very positive value..very high dat is 134... Which shud nt b more XXXXXXX 10... XXXXXXX she asked me to go for rubella IGg avidity test...which also comes out to b 60.8 against 40... Dat is also very high...n may cause very serious disorders to d baby...now she says to repeat the avidity test after 1 month...to confirm whether to go ahead or not...now plz tell me or suggest me shud I go ahead or shud I carry dis baby...becizeduring 4rth month it's very risky to go for abortion...z der any vaccination to cure dis problem??? Plz help me m very panic...
doctor
Answered by Dr. Sameer Kumar (36 minutes later)
Brief Answer:
EXPLAINED...in detail...whats the IgM levels?

Detailed Answer:
hello,
Thanks for the query to hcm,
You are presently at 16 weeks + 4 days with IgG rubella positive which indicates an old infection. But equally important is the IgM levels also.
An avidity test if is again high indicates an old infection prior to pregnancy and hence it should not be affecting the pregnancy at all.
The titres should be measured 3 weekly hence as precaution.
Levl 2 scan would be done in another week between 18-20 weeks which shall indicate if tehre has been any congenital anomaly due to rubella morphologically.
Else you may opt for amniocentesis to confirm IgM rubella antibodies in the fetal amniotic fluid which if high shall indicate that the baby is infected and shall require termination.
Otherwise , if IgM is negative then a conservative approach may be adopted hence of observation and screening depending on the amniocentesis, level 2 scan and 3 weekly titres reports hence.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sameer Kumar (5 minutes later)
My IGm value found to be 0.31 I.e negetiv...n yes I need to test my level 1 next weak..
doctor
Answered by Dr. Sameer Kumar (22 minutes later)
Brief Answer:
answered

Detailed Answer:
Hello,
If IgM is negative then its not a recent infection at all and IgG antibodies have been formed in the body following old infection probably before pregnancy and hence shouldn't affect the foetus .
However a surveillance protocol as mentioned should be followed ---
amniocentesis, level 2 anomaly scan and 3 weekly titres.
Pregnancy can be legally terminated till 20 weeks of pregnancy and anytime if the foetus is abnormal. So go through the screening and relax, chances are unlikely that foetus should be affected with congenital rubella syndrome.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sameer Kumar (1 hour later)
Dat means I dnt need to worry?? I mean der will b d surity dat baby will b fin n normal..
Bt wt if rubella IGg value comes again wid high positive value after 1 month when i l be running 4 th month...??
Do I need to repeat IGm test??
doctor
Answered by Dr. Sameer Kumar (22 minutes later)
Brief Answer:
answered

Detailed Answer:
Yes, the IgG and IgM tests would have to be repeated 3 weekly hence. As the major organ formation take place in the first 12 weeks , hence if amniocentesis and level2 scan comes out to be normal , then likely that the baby is safe.
Regards
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sameer Kumar

OB and GYN Specialist

Practicing since :2002

Answered : 1782 Questions

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Will Rubella Positive With High Avidity Cause Problems In Pregnancy?

Brief Answer: EXPLAINED...in detail...whats the IgM levels? Detailed Answer: hello, Thanks for the query to hcm, You are presently at 16 weeks + 4 days with IgG rubella positive which indicates an old infection. But equally important is the IgM levels also. An avidity test if is again high indicates an old infection prior to pregnancy and hence it should not be affecting the pregnancy at all. The titres should be measured 3 weekly hence as precaution. Levl 2 scan would be done in another week between 18-20 weeks which shall indicate if tehre has been any congenital anomaly due to rubella morphologically. Else you may opt for amniocentesis to confirm IgM rubella antibodies in the fetal amniotic fluid which if high shall indicate that the baby is infected and shall require termination. Otherwise , if IgM is negative then a conservative approach may be adopted hence of observation and screening depending on the amniocentesis, level 2 scan and 3 weekly titres reports hence. Regards