Would Intake Of Escitalopram, Naltrexone, Prazosin And Ziprasidone Have Contributed To Testing Positive For High Rates Of Oxycodone?

Posted on Mon, 18 Jul 2022

Question: Ok, daughter in law recently tested positive for high rates of oxycodone. her meds are escitalopram one and one half pills once daily, naltrexone 50mg once daily, prazosin 1mg once daily ziprasodine 40mg once daily and ziprasidone 40mg once daily, and no, that is not a typo. Would this have contributed to that?

Answered by Dr. Dr. Matt Wachsman (23 minutes later)

Brief Answer:
well... there are a few interesting points here.

Detailed Answer:

Hi,

First, it depends on the type of testing. The cheaper and more common dipstick method is prone to error. They can be mis-read. Sometimes positives occur without it being clear what caused them. THEN, on the much more accurate mass spectroscopy test, there would be breakdown products of the oxycodone. I frequently have bad lab preppers where there is an ultra small amount of a drug like oxycodone or fentanyl BUT there is zero of the drugs' breakdown products. This just cannot occur unless the lab made an error.

But that isn't the most interesting issue here: she is on a blocker of narcotics. The naltrexone is generally given more than once a day BUT it still should block oxycodone if it is taken. Seems very odd.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Matt Wachsman (7 minutes later)

Thank you for your time.

Answered by Dr. Dr. Matt Wachsman (1 minute later)

Brief Answer:
You are quite welcome

Detailed Answer:

Hi,

Gas chromotography-mass spect. should cost 300 at the most and would show the real results. It can also be used on hair to show a pattern of use over the entire time it took the hair to grow.

Regards

Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar