I Have Skin Itching So I Have Consulted With Allergy

Posted on Fri, 12 Feb 2021

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Fri, 12 Feb 2021 Answered on

Fri, 21 Feb 2025 Last reviewed on

Question : i have skin itching so i have consulted with allergy specialist . My IGE test value is 3542 so doctor asked me to consult with hematologist

Answered by Dr. Shailja Puri (3 hours later)

Brief Answer:
Report shows allergy,high light chains suspicious for plasma cell dyscrasia

Detailed Answer:
Hello,

The blood reports show elevated Total Ig E which indicates an allergic process in body.
Itching is probably due to allergic reaction.
Specific Ig E is against cat dander and D pteronyssi - this suggests that you are allergic against these two agents.
Management involves avoidance of the causative agent and anti-histaminics to reduce the symptoms of allergy.
In addition, there is elevation of light chains- kappa and lambda.
Elevation of light chains can be due to plasma cell dyscrasia.
Thus, plasma cell dyscrasia needs to be ruled out.
I suggest you to consult your hematologist and get serum protein electrophoresis to rule out plasma dyscrasia.
The fasting blood glucose is also high. This could be indicative of diabetes mellitus.
I suggest you to get it repeated once and consult your physician.

In case you have more queries, I will be glad to answer.

Thanks and take care
Dr Shailja Puri

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Shailja Puri (16 hours later)

I had discussed with internal medicine doctor and he said values are high because of allergy . proteins test graph is normal so hematologist not required . Do you still wants me to go to Hematologist ?

Answered by Dr. Shailja Puri (2 hours later)

Brief Answer:
The light chain proteins may be repeated after the allergy is under control

Detailed Answer:
Hello and welcome again,
There is a possibility that light chain proteins are raised due to underlying allergic process.
Since, the ratio of light chains is normal, possibility of plasma cell dyscrasia is low.
However, I suggest you to repeat these investigations once the allergic process is under control.

Thanks and take care
Dr Shailja Puri

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Shailja Puri (2 hours later)

Hi , I had visited Hematologist and he said no need to do further testing as its normal because if only one is high ( lambada or kappa test ) then we need to check plasma cell else not required . As per Hematologist , ration is normal so no need to go for further investigation . he has not given any medicine . now you please tell me which medicine i should take to reduce allergy ?

Answered by Dr. Shailja Puri (23 hours later)

Brief Answer:
Allergy can be managed by anti-histaminic drugs

Detailed Answer:
Hello and welcome again,
The symptoms of allergy can be controlled by anti-histaminic drugs.
However, it is best to avoid the allergen because the symptoms remain till you will be in contact with allergen.

Thanks and take care
Dr Shailja Puri

Above answer was peer-reviewed by : Dr. Prasad