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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Am Diabetic, High Fasting Sugar Level, Taking Metformin. Please Advise

Hi, I am 58 year s old and diabetic, since last few days my fasting sugar level is constantly coming above 150 mg/dl. I am taking Metformin 850 mg tablets 3 times a day. Pleas advise. Regards
Mon, 15 Apr 2013
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Diabetologist 's  Response
DEAR SIR/MADAM

THE IMPAIRED FASTING GLUCOSE IS MAINLY DUE TO TWO REASONS.

1. INCREASED HEPATIC GLUCOSE OUTPUT.
2. DECREASED BASAL INSULIN SECRETION.

THESE MIGHT BE DUE TO UNOPPOSED ACTION ON GLUCOGON HORMONE.

TAKING METFORMIN 850 MG THREE TIMES A DAY DECREASES THE HEPATIC GLUCOSE OUTPUT BUT NEVER INCREASES THE BASAL INSULIN SECRETION.

WHAT IS SUGGEST IS TO MAKE METFORMIN 500 MG TWO TIMES A DAY WITH TAB. GLIMEPERIDE 1 MG ONE TIME A DAY.

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Am Diabetic, High Fasting Sugar Level, Taking Metformin. Please Advise

DEAR SIR/MADAM THE IMPAIRED FASTING GLUCOSE IS MAINLY DUE TO TWO REASONS. 1. INCREASED HEPATIC GLUCOSE OUTPUT. 2. DECREASED BASAL INSULIN SECRETION. THESE MIGHT BE DUE TO UNOPPOSED ACTION ON GLUCOGON HORMONE. TAKING METFORMIN 850 MG THREE TIMES A DAY DECREASES THE HEPATIC GLUCOSE OUTPUT BUT NEVER INCREASES THE BASAL INSULIN SECRETION. WHAT IS SUGGEST IS TO MAKE METFORMIN 500 MG TWO TIMES A DAY WITH TAB. GLIMEPERIDE 1 MG ONE TIME A DAY.