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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are Adova And Gonal F Effective In Treatment Of Infertility?

Hi there, I am 34 year and me and mu husband are trying for a child since long, 1.5 years back we started treatment. I am a PCOD patient. At first dr suggested and got all tests done. All tests are normal for both of us. for the 1st 3 months dr gave me ovulation tablets and ask for normal try. (Nov - feb) Later in March Dr suggested to do Laproscopy (done in April) after which she asked us to take a break for 2 months. In July, Aug and Sep we did IUI (Siphene + Folligraf injection + Siphasi 10000 iu) but no positive response, for October and November it was a break time again as the endo lining was not shedding properly. Today, dr. has started Adova 1 mg and has asked to take Gonal F injection on day 3 and 5 and if needed on day 7. Another trail for and IUI. Are we on the right track and why there is no outcome till now. what is the possibility with the change of medicine. what are the chances of getting positive result. else the doctors have told to move on to IVF. Please suggest a remedy or solution.
Mon, 25 Apr 2016
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Infertility Specialist,  's  Response
Hello, thanks for the query. I understand your disappointment regarding unsuccessful treatment so far. Let me guide you through treatment and success rates.
It helps if you understand the chances of pregnancy around the time of ovulation by natural method is only 8 to 10% per cycle.
This pregnancy rate is increased to 12 to 15% per cycle when medication is used to get more than one egg in a cycle ( superovulation) which is again combined with iui. At least 50% of the people will be able to conceive by the end of 4 cycles of iui failing which the chances of conception in further cycles of iui is not any higher than before. And hence its not advisable to continue iui cycles for more than 6 cycles.
Ivf can come up as next best available option as it allows to harvest multiple eggs and freeze excess embryos. It also allows your doctor to evaluate the quality of eggs and embryo and transfer it to the uterus. The chances of conception in an ivf cycle can be 45 to 50%. You have seemingly followed right steps. Good luck with your treatment.
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Are Adova And Gonal F Effective In Treatment Of Infertility?

Hello, thanks for the query. I understand your disappointment regarding unsuccessful treatment so far. Let me guide you through treatment and success rates. It helps if you understand the chances of pregnancy around the time of ovulation by natural method is only 8 to 10% per cycle. This pregnancy rate is increased to 12 to 15% per cycle when medication is used to get more than one egg in a cycle ( superovulation) which is again combined with iui. At least 50% of the people will be able to conceive by the end of 4 cycles of iui failing which the chances of conception in further cycles of iui is not any higher than before. And hence its not advisable to continue iui cycles for more than 6 cycles. Ivf can come up as next best available option as it allows to harvest multiple eggs and freeze excess embryos. It also allows your doctor to evaluate the quality of eggs and embryo and transfer it to the uterus. The chances of conception in an ivf cycle can be 45 to 50%. You have seemingly followed right steps. Good luck with your treatment.