Are Lupron And Flutamide An Effective Alternative Hormonal Treatment For Prostate Cancer, Rising PSA And Bone Metastases After Refusing Orchiectomy?

The patient is a 55-year-old male with adenocarcinoma of the prostate. He had a TURP 1 year ago for presumed prostatic hyperplasia, but tissue fragments examined by a pathologist revealed a poorly differentiated adenocarcinoma. He received local irradiation to the prostate; however, PSA levels increased to 10 (normal is less than 4). A bone scan showed bony metastases. Bilateral orchiectomy was advised, but refused. Alternative hormonal treatment with Lupron and flutamide to decrease testosterone production will be offered.