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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are Doctors Aware Of Any Potential Negative Side Effects Of Garcinia Cambogia Supplement?

Hi, I've seen a lot of hype over Garcinia Cambogia for weight loss. Advertisements stress that fact that it is totally safe to use (because it is "all natural", but so is deadly nightshade, etc.). Are doctors aware of any potential negative side effects of this supplement? Thanks
Wed, 7 Dec 2016
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Addiction Medicine Specialist 's  Response
Well, first it is the classic positive/negative mistake: assuming a system requires an addition when it is a subtraction. There are many examples. The US soccer women do very much better than the men. People are looking for what the women have that the men don't when it is a LACK of ability in the women's soccer in the rest of the world and not a positive thing the women have. In addictions, it is always a REMOVAL of compulsions or other mental components leading to over-use or over-eating. And yet, there are only two books on the diet shelf that deal with this; one of them I wrote.
https://www.YYYYYYYY.com/Way-Devil-Diet-Matt-YYYYYYY/YYY/0692496157

To answer the question.
1) you often get snake oil when purchasing snake oil. The compound is not tested as doing squat.
"Although several studies have found that the administration of G. cambogia extracts is associated with body weight and fat loss in both experimental animals and humans, we should be cautious when interpreting the results as other randomized, placebo-controlled clinical trials have not reported the same outcomes. Furthermore, most studies in humans have been conducted on small samples and mainly in the short term. None of them have shown whether these effects persist beyond 12 weeks of intervention. "
So, it isn't clear it does anything. Furthermore the studies that show it were sorta kinda fraudulent.
https://www.YYYY.YYY.YYY.YYYY/YYYYYY/27757272
Here's the scam. It's POST-STUDY creativity. If I get a pack of cards and say the fourth and fifth cards are clubs and they turn out to be that's slightly amazing. If I do the same thing 5 million times and only show you the one time it worked, well, it's amazing because it should have happened about 100,000 times, but otherwise not so amazing. If I LOOK at the cards THEN put them back and then say the fourth and fifth are clubs, not so amazing. They did a LOT of potential looks for ANY benefit and just report the ONE that worked.

And, most of the commercial preparations have cheap stuff (grape juice maybe) and not the expensive fruit. They lie about what is in it.
https://www.YYYYi.YYY.YYYY.gov/YYYYYY/27702395

The stuff is a fruit. It isn't what's in the product anyway. It hasn't been really studied. So, no, no toxicity found because it hasn't been looked for.
Thankfully it doesn't actually work and you aren't actually getting it.
It is supposed to work by stopping the kreb's cycle--the main metabolic machinery giving energy.
You really want to stop all the energy machinery ? ..cyanide does similar stuff. A previous very very effective weight loss pill did a related effect
https://en.YYYYYYYYorg/wiki/2,4-YYYYYYYYYYYYY
related to cyanide......fatal aspirin overdoses....etc.
FDA suppressed this very effective drug (after it killed a bunch of people; but they got thin!!! well, skeletal...)
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Are Doctors Aware Of Any Potential Negative Side Effects Of Garcinia Cambogia Supplement?

Well, first it is the classic positive/negative mistake: assuming a system requires an addition when it is a subtraction. There are many examples. The US soccer women do very much better than the men. People are looking for what the women have that the men don t when it is a LACK of ability in the women s soccer in the rest of the world and not a positive thing the women have. In addictions, it is always a REMOVAL of compulsions or other mental components leading to over-use or over-eating. And yet, there are only two books on the diet shelf that deal with this; one of them I wrote. https://www.YYYYYYYY.com/Way-Devil-Diet-Matt-YYYYYYY/YYY/0692496157 To answer the question. 1) you often get snake oil when purchasing snake oil. The compound is not tested as doing squat. Although several studies have found that the administration of G. cambogia extracts is associated with body weight and fat loss in both experimental animals and humans, we should be cautious when interpreting the results as other randomized, placebo-controlled clinical trials have not reported the same outcomes. Furthermore, most studies in humans have been conducted on small samples and mainly in the short term. None of them have shown whether these effects persist beyond 12 weeks of intervention. So, it isn t clear it does anything. Furthermore the studies that show it were sorta kinda fraudulent. https://www.YYYY.YYY.YYY.YYYY/YYYYYY/27757272 Here s the scam. It s POST-STUDY creativity. If I get a pack of cards and say the fourth and fifth cards are clubs and they turn out to be that s slightly amazing. If I do the same thing 5 million times and only show you the one time it worked, well, it s amazing because it should have happened about 100,000 times, but otherwise not so amazing. If I LOOK at the cards THEN put them back and then say the fourth and fifth are clubs, not so amazing. They did a LOT of potential looks for ANY benefit and just report the ONE that worked. And, most of the commercial preparations have cheap stuff (grape juice maybe) and not the expensive fruit. They lie about what is in it. https://www.YYYYi.YYY.YYYY.gov/YYYYYY/27702395 The stuff is a fruit. It isn t what s in the product anyway. It hasn t been really studied. So, no, no toxicity found because it hasn t been looked for. Thankfully it doesn t actually work and you aren t actually getting it. It is supposed to work by stopping the kreb s cycle--the main metabolic machinery giving energy. You really want to stop all the energy machinery ? ..cyanide does similar stuff. A previous very very effective weight loss pill did a related effect https://en.YYYYYYYYorg/wiki/2,4-YYYYYYYYYYYYY related to cyanide......fatal aspirin overdoses....etc. FDA suppressed this very effective drug (after it killed a bunch of people; but they got thin!!! well, skeletal...)