Are Pelvic Twinges, Fatigue And Dark Nipples Indicative Of Pregnancy?

I am a 28 year old married woman. My husband and I have been trying to conceive for nearly five years. We got pregnant in 2012 and the day I found out I was pregnant I had a miscarriage. I am also a Type 1 Diabetic. But we have tried so many things to try and get pregnant. We are seeing a fertility specialist in August so in the mean time I thought I would try using fertility vitamins, prenatal vitamins and Natural progesterone cream. According to my cycle app I use I won t start my period for 12 days which I think is off. I think I should be starting in a little over a week, so still early for pregnancy tests, although I tried a 6 days sooner anyway. Lately my nipples have been sore to the tuch. I m get pelvic twinges, breasts feel fuller, nipples darker, and extreme fatigue. what are the chances this is because of the progesterone cream. I don t want to get my hopes up if these symptoms are only due to the progesterone cream.