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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Betha-Thal Minor And G6PD Deficient. Done CBC Test Showed Hypochromic, Ovalocytes. Is It Myelofibrosis Or Dysplasia ?

Hi,

I'm a 24 year old male, Beta-Thal minor and G6PD deficient in an otherwise healthy body. No chronic diseases, no surgeries, no medication, no transfusion history .. Everything is normal. I did a routine CBC showed my Hg is 13, WBC 5, platt 271 .. MCV 58, MCH 18 .. PS showed Hypochromia, few Ovalocytes, and tear drop cells .. I'm concerned about the tear drop cells.. Could myelofibrosis / dysplasia occur in my age .. should i get a marrow Bx or aspirate .. Thanks
posted on Sun, 26 May 2013
Twitter Tue, 4 Jun 2013 Answered on
Twitter Wed, 5 Jun 2013 Last reviewed on
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General & Family Physician,  's  Response
Hi and thanks for using this panel.
I am so so sorry about what you are experiencing.

I know how scared you are about this. Every other person would be, too.

Everything is consistent with what you have but for the tear drop cells. Because you get to do routine blood smears, you may want to wait and see what the next ones have on them. If this tear drop cells persist, then i may side with you to go in for some more aggressive testing. For now, i will not encourage you to unless i get some more information that warrants it.

At your age, these pathologies are rare but medicine never give absolute cut offs. Stay calm and wait for the next routine test, maybe in 3-6months.

Hope this helps or at least provides some guidance.
Feel free to return with more questions.
Wish you good health
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Betha-Thal Minor And G6PD Deficient. Done CBC Test Showed Hypochromic, Ovalocytes. Is It Myelofibrosis Or Dysplasia ?

Hi and thanks for using this panel. I am so so sorry about what you are experiencing. I know how scared you are about this. Every other person would be, too. Everything is consistent with what you have but for the tear drop cells. Because you get to do routine blood smears, you may want to wait and see what the next ones have on them. If this tear drop cells persist, then i may side with you to go in for some more aggressive testing. For now, i will not encourage you to unless i get some more information that warrants it. At your age, these pathologies are rare but medicine never give absolute cut offs. Stay calm and wait for the next routine test, maybe in 3-6months. Hope this helps or at least provides some guidance. Feel free to return with more questions. Wish you good health