Can Atenolol, Lotrel And Diovan Be Taken Along With Welchol?

I have just been told to get a prescription for Welcohl and after reading some of the user reviews I am terrified to stat with this medication. In the past I have taken statins which I had to stop because of leg pain cramping and tiredness. Currently I am taking metaformin 2 times a day and blood pressure meds atenol, Lotrel & diovan, in addition to many supplements such as Vitamin c, d, multi vitamin, lutein, & prevagen. Are any of these meds capable of interacting badly with the Welcohl. Oops, forgot I also have hemmorhoids, is that a problem? I am a 78 year old women, overweight and I do exercise faithfully four times a week for about hour each time. Is there a risk of cramping and fatigue in my legs which I experienced with statins? Also is there a preferred way to take Welcohl each day tog et the most beneficial results?