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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Benedryl Ease The Symptoms Of Fungal Skin In A Person With Renal Failure?

Hi, I am a caregiver and have a client that has renal failure. No treatment that he is doing due to he is in 90's and doesn't want to. He has a rash constantly and at one point the doctor had said it was fungus of the skin. Treated twice but no results. We have been giving him Benedryl daily and its not working. My questions is does the benedryl get desolved in the stomach or does it go through a process that isn't being processed through the kidneys?
Tue, 23 Jun 2015
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General & Family Physician,  's  Response
Dr. Hanif warmly Welcomes you!

Thanks for consulting at my virtual clinic. I have carefully worked through your case, and I can realize your health worries. Being your physician, I assure you not to worry as I will take care all of your medical concerns.
 
Benadryl goes through the liver for its metabolism theough Cytochrome P-450 named enzyme pathway. Kidney is spared in this way.

Some drugs interact with bendryk like MAO Inhibitors( just to put an example, may be he isn't taking it). And this interaction may make it less effective.

For fungal infections he needs Hydrocortisone/Clotrimazole cream to apply topically. Benadryl is just to give relief from associated itching.


Hope it helps. If you need further, detailed and quick assistance related to any health issues in future, feel free to 'ask me a question' directly from my profile.

Have a wonderful time ahead.
 

Best Regards!

DR. MUHAMMAD M. HANIF

USA
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Can Benedryl Ease The Symptoms Of Fungal Skin In A Person With Renal Failure?

Dr. Hanif warmly Welcomes you! Thanks for consulting at my virtual clinic. I have carefully worked through your case, and I can realize your health worries. Being your physician, I assure you not to worry as I will take care all of your medical concerns.   Benadryl goes through the liver for its metabolism theough Cytochrome P-450 named enzyme pathway. Kidney is spared in this way. Some drugs interact with bendryk like MAO Inhibitors( just to put an example, may be he isn t taking it). And this interaction may make it less effective. For fungal infections he needs Hydrocortisone/Clotrimazole cream to apply topically. Benadryl is just to give relief from associated itching. Hope it helps. If you need further, detailed and quick assistance related to any health issues in future, feel free to ask me a question directly from my profile. Have a wonderful time ahead.   Best Regards! DR. MUHAMMAD M. HANIF USA