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Can Contrave And Hydrocodone Be Taken Together?
My doctor gave me a prescription for contrave yesterday to help with weight loss. She also has me on hydrocodone for moderate to severe chronic pain post cervical laminectomy/ corpectomy surgeries. I take 4-6 10 mg hydrocodone daily. I really want to try contrave as my doctor raved about it but I am concerned about mixing it with the pain medicine that I need just to function daily. I am permantely disabled and can t exercise ( except in water) which I do. Should I be concerned about mixing the two? She didn t seem to be.
Mon, 30 Mar 2020
Hi,
It is not advisable to take these two medications together. Contrave is a combination of an opioid antagonist (naltrexone) and an antidepressant (bupropion) commonly prescribed for the treatment of obesity along with lifestyle modifications. Although rare however seizure may occur as a side effect of bupropion and when taken along with other medications that can also cause seizures such as hydrocordone the risk of seizures may increase many folds. You may be more susceptible if you are elderly, undergoing alcohol or drug withdrawal, and have a history of seizures.
Besides, taking naltrexone along with hydrocodone is also not recommended. Naltrexone can block the effects of hydrocodone and make the medication less effective in relieving your severe chronic pain. Moreover, if you take hydrocodone for a week or longer naltrexone can also precipitate withdrawal symptoms. So, in view of the above I advise you not take these two medications together and ask your doctor for an alternate effective but a safer medication to treat both the conditions.
Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali, General & Family Physician
It is not advisable to take these two medications together. Contrave is a combination of an opioid antagonist (naltrexone) and an antidepressant (bupropion) commonly prescribed for the treatment of obesity along with lifestyle modifications. Although rare however seizure may occur as a side effect of bupropion and when taken along with other medications that can also cause seizures such as hydrocordone the risk of seizures may increase many folds. You may be more susceptible if you are elderly, undergoing alcohol or drug withdrawal, and have a history of seizures.
Besides, taking naltrexone along with hydrocodone is also not recommended. Naltrexone can block the effects of hydrocodone and make the medication less effective in relieving your severe chronic pain. Moreover, if you take hydrocodone for a week or longer naltrexone can also precipitate withdrawal symptoms. So, in view of the above I advise you not take these two medications together and ask your doctor for an alternate effective but a safer medication to treat both the conditions.
Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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