Hello dear Understand your concern Yes you can take the duphaston during the pregnancy. You can also use suppository like cyclogest for better effect instead of duphaston. It generally given in high risk pregnancy and in pregnancy with low progesterone level. It prevent the miscarriage and promote the growth of baby. Take under the advice of gynecologist and go for regular follow up. Astymine forte contain vitamin, mineral and amino acid. It also help in maintain and promote the growth of the baby in high risk of pregnancy. So do not worry both drugs should be taken safely with regular follow up to gynecologist. Hope this may help you and Contact HCM for any additional query. Best regards Dr. Sagar