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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can I Take Indomethacin To Help With The Pain After Total Knee Replacement?

Hi! 1 month ago I had a total knee replacement. I have been taking 300mg- 2xday gabapentin and 50mg- 4xday tramadol w/oxycondone 2@325mg every 6 hrs for pain. Can I also take indomethacin 75mg. I am trying to decrease the oxycondone to 1 every 6 hrs but it doesn t seem to be enough. Can I take the indomethacin to help with the pain??
Thu, 28 Sep 2017
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Addiction Medicine Specialist 's  Response
good luck with that. It is perhaps the most powerful anti-inflammatory and very few people have inflammation 1 month after the surgery. the risk of the aspirin like drug having any bad effect on the wound is about zero. BUT there is certainly some risk of ulcer or effects on the vascular system in general. Indo works differently than the other drugs and would add to their effect if it worked. I am just doubtful about that.
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Can I Take Indomethacin To Help With The Pain After Total Knee Replacement?

good luck with that. It is perhaps the most powerful anti-inflammatory and very few people have inflammation 1 month after the surgery. the risk of the aspirin like drug having any bad effect on the wound is about zero. BUT there is certainly some risk of ulcer or effects on the vascular system in general. Indo works differently than the other drugs and would add to their effect if it worked. I am just doubtful about that.