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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can I Undergo Fertility Treatment While Using Heparin Due To Protein S Deficiency?

I would like to know if I would be able to use or under go a fertility treatent using drugs while using heparin due to Protein S Deficiency and repeat Pulmonary Ebolism having had three prior C-Sections. Have been having irregular periods of 2-3 times a years since y last C-section delivery in 2006. Have not gotten pregnant since and have been wanting to have my final child (a girl) for the past 4 years with no success.
posted on Sat, 26 Jan 2013
Twitter Tue, 29 Jan 2013 Answered on
Twitter Tue, 29 Jan 2013 Last reviewed on
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OBGYN,  's  Response
Hello ,
Thanks for the query,

Protein S levels fall progressively during pregnancy.
Heparin is a drug which reduces chances of clotting and pulmonary embolism.

Drugs like clomiphene citrate can be taken with Heparin.

Protein S deficiency causes 10 fold increased risk of thrombosis.

Venous thromboembolism develops in 60-80% of patients with Protein S deficiency.

So think before you plan for your next pregnancy.

Hope this helps,
regards,
Dr Nilofer

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Can I Undergo Fertility Treatment While Using Heparin Due To Protein S Deficiency?

Hello , Thanks for the query, Protein S levels fall progressively during pregnancy. Heparin is a drug which reduces chances of clotting and pulmonary embolism. Drugs like clomiphene citrate can be taken with Heparin. Protein S deficiency causes 10 fold increased risk of thrombosis. Venous thromboembolism develops in 60-80% of patients with Protein S deficiency. So think before you plan for your next pregnancy. Hope this helps, regards, Dr Nilofer