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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Ramipril Cause High INR Levels?

Hi, I was taking warfarin 5mg. 3days and warfarin 2.5 other 4 days. My heart Dr. put me on Ramipril 2.5 mg oral oce daily. The first INR test I had afer taking new drug was about two weeks later. The test showed a result of 7.6. I explained the drug change to the testing person andshe said Ramipril could not be the cause even though I told her I had no other new drugs and my food diet is always the same sait has been for 2 years and that is 4 or 5cans of Jevity 355calories each per day. When I rlated all again and she said it was not the Ramipril. II asked how she knew and she curtly ttold me she knew! I stopped the Ramipril and the warfarin was stopped for 2 days and then resumed and previous dosage. The next INR test was 1.4 and I am currently on old warfarin dosage but have not resume the Ranipril.I will have another testin 4 days. I do not know if she has passed this ifo to my cardiologist. Thank you for any advice you can give. P.S. I found one reference that quoted FDA data that showen rise of INR, especially at age 40 on up and I an 78yeqrs old.
Mon, 15 Oct 2018
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General & Family Physician 's  Response
Hello,

Please see that Ramipril does not increase International Normalized Ratio (INR).

Hope I have answered your query.
Let me know if I can assist you further.

Warm Regards,
Dr Varinder Joshi.
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Can Ramipril Cause High INR Levels?

Hello, Please see that Ramipril does not increase International Normalized Ratio (INR). Hope I have answered your query. Let me know if I can assist you further. Warm Regards, Dr Varinder Joshi.