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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Ranitidine And Loratadine Be Taken Together For Rashes And Hives?

My daughter broke out with rash like hives ( Wednesday morning) red and itchy under left side of jaw and swelling under jawline, pain started on right side but centered on left side. She just finished taking a packet of methylprednisolone tablets (2nd time to take them within a 2 month period) to treat a sports injury. She was also taking Augmentin 875mg twice a day (still has two pills left to take) for a chronic cough and ear problems of which this is second time on antibiotics; she took a z pack in early march. Her stress level is high, she graduates high school in two weeks and will finish college classes next week. She did see her sports medicine doctor and a CNP. They recommended Benadryl 50 mg every 8 hours and hydrocortisone cream for rash. In the meantime the Benadryl and hydro.cream has made no difference. The rash looks like welts and the swelling under jaw is worse. The CNP prescribed ranitidine 150 mg 1 daily for 14 days and loratadine 10 mg one daily. and recommended using Flonase daily. Why ranitidine? If she s taking Benadryl 50 mg why take the loratadine as well?
Wed, 15 Mar 2023
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General & Family Physician 's  Response
Hi,

Yes, Ranitidine (an H2 blocker used for acid reflux) and Loratadine (an antihistamine used for allergy symptoms) can be taken together for rashes and hives as they work through different mechanisms of action.

Ranitidine may be prescribed to relieve symptoms of itching and rash associated with hives because it blocks the release of histamine from cells, which can help reduce swelling, itching, and redness. Histamine is released during an allergic reaction and can cause symptoms such as itching, rash, and hives.

Loratadine, on the other hand, works by blocking the action of histamine at the receptor sites, which can help relieve symptoms of allergies such as sneezing, itching, runny nose, and hives. It is often used in combination with other medications, such as Ranitidine, to provide additional relief from allergy symptoms.

It is important to follow the dosing instructions provided by the healthcare provider, and not exceed the recommended dosage for either medication. It is also important to be aware of any potential side effects and to notify the healthcare provider if any adverse effects are experienced.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Priyanka, General & Family Physician
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Can Ranitidine And Loratadine Be Taken Together For Rashes And Hives?

Hi, Yes, Ranitidine (an H2 blocker used for acid reflux) and Loratadine (an antihistamine used for allergy symptoms) can be taken together for rashes and hives as they work through different mechanisms of action. Ranitidine may be prescribed to relieve symptoms of itching and rash associated with hives because it blocks the release of histamine from cells, which can help reduce swelling, itching, and redness. Histamine is released during an allergic reaction and can cause symptoms such as itching, rash, and hives. Loratadine, on the other hand, works by blocking the action of histamine at the receptor sites, which can help relieve symptoms of allergies such as sneezing, itching, runny nose, and hives. It is often used in combination with other medications, such as Ranitidine, to provide additional relief from allergy symptoms. It is important to follow the dosing instructions provided by the healthcare provider, and not exceed the recommended dosage for either medication. It is also important to be aware of any potential side effects and to notify the healthcare provider if any adverse effects are experienced. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician