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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Rosuvastatin Cause Elevated SGPT Levels?

I am a Diabitic and hypertension. I am taking Rosuvastati 20 mg.and Glimiperide 1 + Mrtformin 500 combined and olmesar tan 20 + amlodepin 5 combine. My Lipids sugar and Bp is normal. But my Sgpt is 55 yo 72 in last 5 years. I am taking Alcohol once in a week about 80 ml only. Should I stop alcohol?? High Sgpt is due to Rosuvastatn??
Wed, 28 Jun 2017
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General & Family Physician,  's  Response
Hi,
Thanks for posting in HCM.
I understand your concern.
Rosuvastatin is used for lowering high cholesterol and triglycerides. It is an HMG-CoA reductase inhibitor, also known as a "statin".
Commonly reported side effects of use of rosuvastatin include: myalgia (muscle pain and muscle cramps).
It is not known to cause hepatocellular damage leading to rise in SGPT (AST) levels.
It seems the rise in SGPT levels could be due to alcohol intake as it is a known to have hepatotoxic effect. It would be better to stop alcohol intake so as to prevent further liver damage.
Kindly take regularly antioxidant supplements containing Vitamin E, Selenium, Alpha Lipoic acid and Vitamin C, which helps to keep your liver tissue healthy.
Hope the information provided helps.
Wish you good health.
Regards,
Dr.Ashakiran.S.,
MBBS., MD.
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Can Rosuvastatin Cause Elevated SGPT Levels?

Hi, Thanks for posting in HCM. I understand your concern. Rosuvastatin is used for lowering high cholesterol and triglycerides. It is an HMG-CoA reductase inhibitor, also known as a statin . Commonly reported side effects of use of rosuvastatin include: myalgia (muscle pain and muscle cramps). It is not known to cause hepatocellular damage leading to rise in SGPT (AST) levels. It seems the rise in SGPT levels could be due to alcohol intake as it is a known to have hepatotoxic effect. It would be better to stop alcohol intake so as to prevent further liver damage. Kindly take regularly antioxidant supplements containing Vitamin E, Selenium, Alpha Lipoic acid and Vitamin C, which helps to keep your liver tissue healthy. Hope the information provided helps. Wish you good health. Regards, Dr.Ashakiran.S., MBBS., MD.