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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can A Course Progynova And Meprate Be Taken Every Month After Removal Of Ovaries?

hello, i had an operation in 2012 in which both of my ovaries were removed because i had benign cysts in my ovaries. since 2013 i was taking progynova 2 mg tablet and meparate 5 mg tablet. i take daily 1 tablet of progynova 2 mg and 1 tablet of meparate 5 mg on 1st ten of every month . is this the right way to take these medicines.
Sat, 2 Sep 2023
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OB & GYN Specialist 's  Response
Hello,

Hormonal replacement is recommended if you have undergone surgical removal of ovaries before 45 years. It is advised to continue until the average age of natural menopause unless you have any contraindications for taking it (contraindications are breast cancer, thrombotic diseases, personal or family history of hormone dependent cancer, liver disease, history of DVT, pulmonary embolism, obesity).

For the initial 1 or 2 years post surgery you may need Progynova of 2 mg dosage, but after that you can reduce the dose to 1 mg. If you have not done hysterectomy then you should take Meprate in the second half of cycle for 12 to 14 days to induce withdrawal bleeding. If you have done hysterectomy then you may not need progesterone. So estrogen in lower dose is taken daily and you will have to add progesterone in the second half of cycle ie from day 14 to 28 and then wait for withdrawal bleeding.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Praseetha Narayanan, OB & GYN Specialist
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Can A Course Progynova And Meprate Be Taken Every Month After Removal Of Ovaries?

Hello, Hormonal replacement is recommended if you have undergone surgical removal of ovaries before 45 years. It is advised to continue until the average age of natural menopause unless you have any contraindications for taking it (contraindications are breast cancer, thrombotic diseases, personal or family history of hormone dependent cancer, liver disease, history of DVT, pulmonary embolism, obesity). For the initial 1 or 2 years post surgery you may need Progynova of 2 mg dosage, but after that you can reduce the dose to 1 mg. If you have not done hysterectomy then you should take Meprate in the second half of cycle for 12 to 14 days to induce withdrawal bleeding. If you have done hysterectomy then you may not need progesterone. So estrogen in lower dose is taken daily and you will have to add progesterone in the second half of cycle ie from day 14 to 28 and then wait for withdrawal bleeding. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Praseetha Narayanan, OB & GYN Specialist