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Dr. Andrew Rynne

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Can A Panic Attack Cause Elevated Troponin Levels, Or Does It Indicate Heart Damage?

Hello doctors, I suffer from panic disorder and agoraphobia born from health anxiety (cardiophobia). I ve been progressing well with therapy and am feeling pretty optimistic about remission. The last time I ever went to the ER back in late 2021, I suffered what I believe to be a panic attack. It was easily the most severe one I had suffered at the time and is what caused the agoraphobia to start. I had every classic symptom as well as a severe feeling of my heart squeezing painfully in my chest, which is what prompted me to go to the ER. The doctors there and my personal cardiologist said I was fine based on my blood work. Here s my question: my HS Troponin levels were 3 ng/L. My understanding is there shouldn t be any troponin in the blood unless damage was done to the heart. Is that true? Or can a panic attack cause an elevation in troponin as well? If it matters, I have no family history of cardiovascular conditions except hypertension. I personally do not have hypertension. I ve also had a stress echo done and my doctor said it was perfectly normal. Thanks for answering! :)
posted on Sun, 10 Sep 2023
Twitter Mon, 28 Jul 2025 Answered on
Twitter Sun, 3 Aug 2025 Last reviewed on
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Cardiologist 's  Response
Hello,

Panic attack can sometimes release excessive adrenaline in the system causing cardiac muscle damage and release of Troponine. This is called Stress cardiomyopathy. Alternatively, baseline Troponine can also be high in certain individual and with certain condition like kidney disease. As your stress echo is normal, you should not worry.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Sameer Maheshwari, Cardiologist
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Can A Panic Attack Cause Elevated Troponin Levels, Or Does It Indicate Heart Damage?

Hello, Panic attack can sometimes release excessive adrenaline in the system causing cardiac muscle damage and release of Troponine. This is called Stress cardiomyopathy. Alternatively, baseline Troponine can also be high in certain individual and with certain condition like kidney disease. As your stress echo is normal, you should not worry. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Sameer Maheshwari, Cardiologist