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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Elevated Levels Of SGOT And SGPT During Third Trimester Cause Fetal Harm?

Hi, I m 33 weeks pregnant. My all parameters like bilirubin total & direct, serum protein,albumin,globulin are in the range. But having high levels of SGOT,SGPT and serum alkaline phosphatase - 132,156,and 458. Will it affect my foetus badly? Please help. I m in big stress. Is there any chance of loosing my baby?
Wed, 28 Oct 2015
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General & Family Physician,  's  Response
Hi & Welcome.
I can understand your concern for the elevated liver enzymes during pregnancy.
Yes, persistently elevated levels of these enzymes can be harmful to the fetus.

After having gone through the history and the results of liver function tests given you seem to have some sort of liver problem.
This could be due to "cholestasis of pregnancy" or "preeclampsia" or viral hepatitis.

You must contact your doctor to correlate these results clinically and a drug like Ursodeoxycholic acid is highly recommended to treat the cholestasis of pregnancy.
Beside, other causes like hepatitis should also be ruled out & you will have to repeat the test and remain under strict follow up of your doctor & get scan of fetus with doppler study. If the levels continue to rise pregnancy is usually terminated by 37 weeks, if it is due to cholestasis of pregnancy only.
Don't worry, everything will be alright.
Take care.







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Can Elevated Levels Of SGOT And SGPT During Third Trimester Cause Fetal Harm?

Hi & Welcome. I can understand your concern for the elevated liver enzymes during pregnancy. Yes, persistently elevated levels of these enzymes can be harmful to the fetus. After having gone through the history and the results of liver function tests given you seem to have some sort of liver problem. This could be due to cholestasis of pregnancy or preeclampsia or viral hepatitis. You must contact your doctor to correlate these results clinically and a drug like Ursodeoxycholic acid is highly recommended to treat the cholestasis of pregnancy. Beside, other causes like hepatitis should also be ruled out & you will have to repeat the test and remain under strict follow up of your doctor & get scan of fetus with doppler study. If the levels continue to rise pregnancy is usually terminated by 37 weeks, if it is due to cholestasis of pregnancy only. Don t worry, everything will be alright. Take care.