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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can I Reduce The Dose Of 'acitrom' If INR Is Raised?

my mother is taking acitrom from last 6 years , daily she was taking 5 mg/day for controlling the pt/inr to 2.5

now she is in oman from last 6 months , after taking this dosage her pt/inr level is going up to 5.5 & some time blood coming from nos

now we reduced the tab to 3 & 4 in alternative days \

is any problem ?pls help
Tue, 2 Sep 2014
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Geriatrics Specialist 's  Response
Hi,
Thanks for asking.
Based on your clinical history and query, my opinion is as follows:
1. High INR increases the risk of bleeding and most of the times, internal bleeding can be critical.
2. If the INR is maintained between 2-3, with reduced dosage, its ok.
3. However, discuss with your health care specialist and also get your INR checked twice to avoid laboratory errors, as 2.5 to 5.5 is a massive difference and other medications may be contributing to variations.

Hope it helps.
Any further queries, happy to help again.
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Can I Reduce The Dose Of 'acitrom' If INR Is Raised?

Hi, Thanks for asking. Based on your clinical history and query, my opinion is as follows: 1. High INR increases the risk of bleeding and most of the times, internal bleeding can be critical. 2. If the INR is maintained between 2-3, with reduced dosage, its ok. 3. However, discuss with your health care specialist and also get your INR checked twice to avoid laboratory errors, as 2.5 to 5.5 is a massive difference and other medications may be contributing to variations. Hope it helps. Any further queries, happy to help again.