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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Immune Deficinecy In Body Cause False Positive For HSV2?

Tested positive for HSV2. However, I do not or have any symptoms or out breaks. I am wondering if it can be a false positive as I have a compromised immune system. I have had two types of chemotherapy due to bone cancer, a bone implant and during the chemo had to have the varicella vaccine as I was exposed to chicken pox at a time my immune system was deficient. I did have chicken pox at the age of 5. As a result, my body never heals and I know I have an immune deficiency. Can this have caused the high rating of a positive test.
posted on Mon, 13 Oct 2014
Twitter Sun, 11 Jan 2015 Answered on
Twitter Mon, 12 Jan 2015 Last reviewed on
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
Depressed immune status is known to cause negative serological tests for various infections.
Thus, the HSV 2 test can be negative in the presence of depressed immune status.
However, a positive HSV 2 test indicates presence of HSV 2 infection.
Thus, you need to consult your physician for further management.

Thanks and take care
Dr Shailja Puri
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Can Immune Deficinecy In Body Cause False Positive For HSV2?

Hello and welcome to HCM, Depressed immune status is known to cause negative serological tests for various infections. Thus, the HSV 2 test can be negative in the presence of depressed immune status. However, a positive HSV 2 test indicates presence of HSV 2 infection. Thus, you need to consult your physician for further management. Thanks and take care Dr Shailja Puri