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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Pain Medications And Steroids Elevate AST And ALT Levels?

My recent blood test for my annual physical had AST at 91 and ALT at 96. Last year they were AST 41 and ALT 60. A couple week prior to the blood test I threw out my back and was given several different pain medications, muscle relaxers and steroids for inflammation. Could that medication have spiked the test results. Regardless, are those levels I should be worried about?
Thu, 26 Nov 2015
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Radiologist,  's  Response
Hello

High ALT and AST may indicate liver injury.
It may be due to many reasons like hepatitis,alcohol intake,altered lipid profile,medicines,auto immune causes etc.
It may be due to medicines side effects in your case.

You may need clinical evaluation and investigations like routine hemogram,random blood sugar,lipid profile,ultrasound of abdomen.
I suggest tablet ursodeoxycholic acid 300 mg tablet twice daily for three months.It helps in regeneration of liver cells.

You may need dose adjustment of medicines.

Get well soon.
Take Care
Dr.Indu Bhushan
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Can Pain Medications And Steroids Elevate AST And ALT Levels?

Hello High ALT and AST may indicate liver injury. It may be due to many reasons like hepatitis,alcohol intake,altered lipid profile,medicines,auto immune causes etc. It may be due to medicines side effects in your case. You may need clinical evaluation and investigations like routine hemogram,random blood sugar,lipid profile,ultrasound of abdomen. I suggest tablet ursodeoxycholic acid 300 mg tablet twice daily for three months.It helps in regeneration of liver cells. You may need dose adjustment of medicines. Get well soon. Take Care Dr.Indu Bhushan