Can pleurisy be genetic? I am 24 yrs old, 5 2, around 120 pounds. I have had problems with my ribs for 9 years now. Sometimes I get very sharp pains in my ribs that only lasts for about 30 seconds to a couple minutes. Sometimes my ribs feel sore, and it gets worse for a couple days but is usually gone on the third or fourth day. It hurts to do anything, feels very sore. We just found out my moms grandma had pleurisy and maybe that s what is wrong with me. Doctors haven t believed me in my town since highschool so I have given up hope on them, but I need to figure out what it is so hopefully when it happens next, I can get something to help.