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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could Elevated ALT And ALP Levels Lead To Lethargy And Weight Gain?

Hi my ALT and ALP have been elevated for several months, highest about 278, both currently at 143. I don t drink or smoke, but do over eat, very much a chocoholic, loving carbohydrates / sugary stuff. I have some fat in my liver and a 4mm gallbladder polyup. I m male 34 bout 5ft 8in height, bout 15 nearly 16 stone; so certainly overweight. Symptoms of severe lethargy have reduced as the serum levels have fallen, which may be drug related; reduced duloxetine down from 120mg per day to 90mg. Curious as to what the cause of the persistently elevated but reducing serum levels is. Can you shed some light? Thanks :)
posted on Sat, 15 Feb 2014
Twitter Tue, 4 Mar 2014 Answered on
Twitter Thu, 6 Mar 2014 Last reviewed on
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Internal Medicine Specialist,  's  Response
Dear Friend
I understy your concern.
I am more worried about your raised liver enzymes.
They should be evaluated.
I advise you to get following investigation:
1. HBsAg
2. Anti HCV Antibody.
3. Complete LFT.
If no cause is found on these investigation s we will do workup for Non Alcoholic Fatty Liver Disease.
Don't take the things lightly.
There is definitely some problem.
Stay Healthy.
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Could Elevated ALT And ALP Levels Lead To Lethargy And Weight Gain?

Dear Friend I understy your concern. I am more worried about your raised liver enzymes. They should be evaluated. I advise you to get following investigation: 1. HBsAg 2. Anti HCV Antibody. 3. Complete LFT. If no cause is found on these investigation s we will do workup for Non Alcoholic Fatty Liver Disease. Don t take the things lightly. There is definitely some problem. Stay Healthy.