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Could Infertility Be Due To Genetic Variation In MTHFR Gene?
Hi. I m 68 years old, and only recently discovered through a blood test that I have the MTHFR (C677T) TT gene. This has answered so many of my questions! Cervical stenosis, Heart Murmur, Infertility, High Blood Pressure, tumor in left side of Thyroid requiring thyroidectomy, terrible reaction to bleach, to name just a few. Right now, I m at a loss to find a good doctor here in the Denver area who can help me. My insurance (Blue Cross Blue Shield) suggests an Internal Medicine doctor. (Also have Medicare) Any suggestions?
Tue, 2 May 2023
Hi,
The MTHFR (C677T) TT gene variant is associated with decreased activity of the MTHFR enzyme, which is important for the proper metabolism of folate and other nutrients. This can result in elevated levels of homocysteine in the blood, which has been associated with an increased risk of certain health problems, including cardiovascular disease, neural tube defects in babies, and some cancers.
There is some evidence to suggest that the MTHFR gene variant may also play a role in infertility. Studies have found an association between the MTHFR (C677T) TT genotype and decreased sperm motility in men, as well as an increased risk of recurrent miscarriage in women. However, it is important to note that infertility is a complex condition with many potential causes, and the MTHFR gene variant is just one of many factors that could contribute.
In terms of finding a doctor, it may be helpful to look for a healthcare provider with experience in genetics or functional medicine. A genetic counselor can also guide how the MTHFR gene variant may impact your health and any potential treatment options.
You can search for a genetic counselor in your area through the National Society of Genetic Counselors website. Additionally, you may want to consider seeking out a naturopathic doctor or integrative medicine practitioner who can work with you on optimizing your nutrition and addressing any underlying health issues.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Priyanka, General & Family Physician
The MTHFR (C677T) TT gene variant is associated with decreased activity of the MTHFR enzyme, which is important for the proper metabolism of folate and other nutrients. This can result in elevated levels of homocysteine in the blood, which has been associated with an increased risk of certain health problems, including cardiovascular disease, neural tube defects in babies, and some cancers.
There is some evidence to suggest that the MTHFR gene variant may also play a role in infertility. Studies have found an association between the MTHFR (C677T) TT genotype and decreased sperm motility in men, as well as an increased risk of recurrent miscarriage in women. However, it is important to note that infertility is a complex condition with many potential causes, and the MTHFR gene variant is just one of many factors that could contribute.
In terms of finding a doctor, it may be helpful to look for a healthcare provider with experience in genetics or functional medicine. A genetic counselor can also guide how the MTHFR gene variant may impact your health and any potential treatment options.
You can search for a genetic counselor in your area through the National Society of Genetic Counselors website. Additionally, you may want to consider seeking out a naturopathic doctor or integrative medicine practitioner who can work with you on optimizing your nutrition and addressing any underlying health issues.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Priyanka, General & Family Physician
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