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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Amlodipine2.5mgm And Hydrochlothiazide 12.5mg Have Any Side Effects?

Im 74yr old ,had angioplasty twice,hypertensive ,taking Bisoprolol7.5mg of for over 15yrs losartan 100mgm od.As the Bp was not under control ,I add amlodipine2.5mgm+hydrochlothiazide 12.5mg od for over 2months.Now the Bp is 120/70mmhg. After adding the later two, I developed eczematous pruritic rashes resembling erythema multiforme and mayalgia+knee pain +blistering ankle oedema. PL advice next course of action,I m not a diabetic.Much obliged .DR MB SALIM
posted on Mon, 25 Apr 2016
Twitter Wed, 4 Mar 2020 Answered on
Twitter Thu, 5 Mar 2020 Last reviewed on
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General Surgeon,  's  Response
Hello,

The amlodipine is known to produce ankle swelling with fluid retention via its adverse effects. The hydrochlorthiazide is associated with multiple electrolyte disturbances as low levels of potassium, sodium, calcium giving clinical symptoms as per the severity basis. However, further management would require consultation with your treating physician, stopping of amlodipine would help great extent at present in your condition. Be cautious to control salt intake in the diet on regular basis.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Bhagyesh V. Patel, General Surgeon
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Do Amlodipine2.5mgm And Hydrochlothiazide 12.5mg Have Any Side Effects?

Hello, The amlodipine is known to produce ankle swelling with fluid retention via its adverse effects. The hydrochlorthiazide is associated with multiple electrolyte disturbances as low levels of potassium, sodium, calcium giving clinical symptoms as per the severity basis. However, further management would require consultation with your treating physician, stopping of amlodipine would help great extent at present in your condition. Be cautious to control salt intake in the diet on regular basis. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon