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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Azathioprine And Allopurinol Cause Joint Pain?

My husband has been taking azothiaprim & allopurinal to treat his active crohn s disease. He has developed painful joints, shortness of breath, fatigue, painful calves, noise in ears, noticable heartbeats/ pulse, and loss of skin color/ pallor from head to toe, some decrease in appetite. He has discontinued the allopurinal, but has not experienced improvement in symptoms yet. What causes the pallor/ pale skin & other symptoms & is this reaction expected to improve with discontinuatiin of the drug?
posted on Tue, 3 Oct 2017
Twitter Wed, 18 Jul 2018 Answered on
Twitter Mon, 23 Jul 2018 Last reviewed on
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General & Family Physician,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

I appreciate your concern.
No, they do not lead to joint pains directly.

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Do Azathioprine And Allopurinol Cause Joint Pain?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. I appreciate your concern. No, they do not lead to joint pains directly. Hope I have answered your query. Let me know if I can assist you further.