I am really sorry for the losses your family have suffered. Dear madam, reasons for oral cancers are many, amongst most common things we eat like, spices and especially chilly, besides the obvious reasons like nicotine (in any form, like chewable tobacco with or without lime). at this point i would like to aknowledge that there is a strong familial prediliction in many cases, as you have already mentioned that the other family members have also been diagnosed with this deadly disease. however besides these factors, chemical level of water and radiation of mobile and internet waves have also been enlisted as the cause of cancer. Dr. Neha Vanza Khare Asst Prof. RKDF Dental College Bhopal